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Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta.
Sylla BS, Hung SC, Davidson DM, Hatzivassiliou E, Malinin NL, Wallach D, Gilmore TD, Kieff E, Mosialos G. Sylla BS, et al. Among authors: hatzivassiliou e. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10106-11. doi: 10.1073/pnas.95.17.10106. Proc Natl Acad Sci U S A. 1998. PMID: 9707608 Free PMC article.
Mutational analysis of TRAF6 reveals a conserved functional role of the RING dimerization interface and a potentially necessary but insufficient role of RING-dependent TRAF6 polyubiquitination towards NF-κB activation.
Megas C, Hatzivassiliou EG, Yin Q, Marinopoulou E, Hadweh P, Vignali DA, Mosialos G. Megas C, et al. Among authors: hatzivassiliou eg. Cell Signal. 2011 May;23(5):772-7. doi: 10.1016/j.cellsig.2010.12.004. Epub 2010 Dec 23. Cell Signal. 2011. PMID: 21185369 Free PMC article.
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