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72 results
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Mathematical model of human growth hormone (hGH)-stimulated cell proliferation explains the efficacy of hGH variants as receptor agonists or antagonists.
Haugh JM. Haugh JM. Biotechnol Prog. 2004 Sep-Oct;20(5):1337-44. doi: 10.1021/bp0499101. Biotechnol Prog. 2004. PMID: 15458315
Physical modulation of intracellular signaling processes by locational regulation.
Haugh JM, Lauffenburger DA. Haugh JM, et al. Biophys J. 1997 May;72(5):2014-31. doi: 10.1016/S0006-3495(97)78846-5. Biophys J. 1997. PMID: 9129805 Free PMC article.
Scratching the (cell) surface: cytokine engineering for improved ligand/receptor trafficking dynamics.
Lauffenburger DA, Fallon EM, Haugh JM. Lauffenburger DA, et al. Among authors: haugh jm. Chem Biol. 1998 Oct;5(10):R257-63. doi: 10.1016/s1074-5521(98)90110-7. Chem Biol. 1998. PMID: 9818145 Review.
Analysis of receptor internalization as a mechanism for modulating signal transduction.
Haugh JM, Lauffenburger DA. Haugh JM, et al. J Theor Biol. 1998 Nov 21;195(2):187-218. doi: 10.1006/jtbi.1998.0791. J Theor Biol. 1998. PMID: 9822563
Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-gamma1 signaling pathway.
Haugh JM, Schooler K, Wells A, Wiley HS, Lauffenburger DA. Haugh JM, et al. J Biol Chem. 1999 Mar 26;274(13):8958-65. doi: 10.1074/jbc.274.13.8958. J Biol Chem. 1999. PMID: 10085141
Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts.
Haugh JM, Huang AC, Wiley HS, Wells A, Lauffenburger DA. Haugh JM, et al. J Biol Chem. 1999 Nov 26;274(48):34350-60. doi: 10.1074/jbc.274.48.34350. J Biol Chem. 1999. PMID: 10567412
Mathematical modeling of epidermal growth factor receptor signaling through the phospholipase C pathway: mechanistic insights and predictions for molecular interventions.
Haugh JM, Wells A, Lauffenburger DA. Haugh JM, et al. Biotechnol Bioeng. 2000 Oct 20;70(2):225-38. Biotechnol Bioeng. 2000. PMID: 10972934
A unified model for signal transduction reactions in cellular membranes.
Haugh JM. Haugh JM. Biophys J. 2002 Feb;82(2):591-604. doi: 10.1016/S0006-3495(02)75424-6. Biophys J. 2002. PMID: 11806904 Free PMC article.
Active EGF receptors have limited access to PtdIns(4,5)P(2) in endosomes: implications for phospholipase C and PI 3-kinase signaling.
Haugh JM, Meyer T. Haugh JM, et al. J Cell Sci. 2002 Jan 15;115(Pt 2):303-10. J Cell Sci. 2002. PMID: 11839782
Kinetic analysis of platelet-derived growth factor receptor/phosphoinositide 3-kinase/Akt signaling in fibroblasts.
Park CS, Schneider IC, Haugh JM. Park CS, et al. Among authors: haugh jm. J Biol Chem. 2003 Sep 26;278(39):37064-72. doi: 10.1074/jbc.M304968200. Epub 2003 Jul 18. J Biol Chem. 2003. PMID: 12871957
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