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Crosslinking and mechanical properties significantly influence cell attachment, proliferation, and migration within collagen glycosaminoglycan scaffolds.
Haugh MG, Murphy CM, McKiernan RC, Altenbuchner C, O'Brien FJ. Haugh MG, et al. Tissue Eng Part A. 2011 May;17(9-10):1201-8. doi: 10.1089/ten.TEA.2010.0590. Epub 2011 Jan 17. Tissue Eng Part A. 2011. PMID: 21155630
Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates.
Haugh MG, Vaughan TJ, Madl CM, Raftery RM, McNamara LM, O'Brien FJ, Heilshorn SC. Haugh MG, et al. Biomaterials. 2018 Jul;171:23-33. doi: 10.1016/j.biomaterials.2018.04.026. Epub 2018 Apr 16. Biomaterials. 2018. PMID: 29677521 Free PMC article.
An in vitro bone tissue regeneration strategy combining chondrogenic and vascular priming enhances the mineralization potential of mesenchymal stem cells in vitro while also allowing for vessel formation.
Freeman FE, Haugh MG, McNamara LM. Freeman FE, et al. Among authors: haugh mg. Tissue Eng Part A. 2015 Apr;21(7-8):1320-32. doi: 10.1089/ten.TEA.2014.0249. Epub 2015 Mar 3. Tissue Eng Part A. 2015. PMID: 25588588
The application of plastic compression to modulate fibrin hydrogel mechanical properties.
Haugh MG, Thorpe SD, Vinardell T, Buckley CT, Kelly DJ. Haugh MG, et al. J Mech Behav Biomed Mater. 2012 Dec;16:66-72. doi: 10.1016/j.jmbbm.2012.10.009. Epub 2012 Oct 27. J Mech Behav Biomed Mater. 2012. PMID: 23149099
Novel freeze-drying methods to produce a range of collagen-glycosaminoglycan scaffolds with tailored mean pore sizes.
Haugh MG, Murphy CM, O'Brien FJ. Haugh MG, et al. Tissue Eng Part C Methods. 2010 Oct;16(5):887-94. doi: 10.1089/ten.TEC.2009.0422. Tissue Eng Part C Methods. 2010. PMID: 19903089
The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering.
Murphy CM, Haugh MG, O'Brien FJ. Murphy CM, et al. Among authors: haugh mg. Biomaterials. 2010 Jan;31(3):461-6. doi: 10.1016/j.biomaterials.2009.09.063. Epub 2009 Oct 9. Biomaterials. 2010. PMID: 19819008
The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen-GAG scaffolds for bone tissue engineering.
Tierney CM, Haugh MG, Liedl J, Mulcahy F, Hayes B, O'Brien FJ. Tierney CM, et al. Among authors: haugh mg. J Mech Behav Biomed Mater. 2009 Apr;2(2):202-9. doi: 10.1016/j.jmbbm.2008.08.007. Epub 2008 Oct 4. J Mech Behav Biomed Mater. 2009. PMID: 19627824
The effect of dehydrothermal treatment on the mechanical and structural properties of collagen-GAG scaffolds.
Haugh MG, Jaasma MJ, O'Brien FJ. Haugh MG, et al. J Biomed Mater Res A. 2009 May;89(2):363-9. doi: 10.1002/jbm.a.31955. J Biomed Mater Res A. 2009. PMID: 18431763
Gene expression by marrow stromal cells in a porous collagen-glycosaminoglycan scaffold is affected by pore size and mechanical stimulation.
Byrne EM, Farrell E, McMahon LA, Haugh MG, O'Brien FJ, Campbell VA, Prendergast PJ, O'Connell BC. Byrne EM, et al. Among authors: haugh mg. J Mater Sci Mater Med. 2008 Nov;19(11):3455-63. doi: 10.1007/s10856-008-3506-2. Epub 2008 Jun 27. J Mater Sci Mater Med. 2008. PMID: 18584120
Temporal and spatial changes in cartilage-matrix-specific gene expression in mesenchymal stem cells in response to dynamic compression.
Haugh MG, Meyer EG, Thorpe SD, Vinardell T, Duffy GP, Kelly DJ. Haugh MG, et al. Tissue Eng Part A. 2011 Dec;17(23-24):3085-93. doi: 10.1089/ten.tea.2011.0198. Epub 2011 Aug 26. Tissue Eng Part A. 2011. PMID: 21870950
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