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332 results
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Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.
Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg MC, Kvien TK, Schnitzer TJ; VIGOR Study Group. Bombardier C, et al. Among authors: hawkey cj. N Engl J Med. 2000 Nov 23;343(21):1520-8, 2 p following 1528. doi: 10.1056/NEJM200011233432103. N Engl J Med. 2000. PMID: 11087881 Clinical Trial.
Response to expression of concern regarding VIGOR study.
Bombardier C, Laine L, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg MC, Kvien TK, Schnitzer TJ, Weaver A. Bombardier C, et al. Among authors: hawkey cj. N Engl J Med. 2006 Mar 16;354(11):1196-9. doi: 10.1056/NEJMc066096. Epub 2006 Feb 22. N Engl J Med. 2006. PMID: 16495387 No abstract available.
Reduced incidence of gastroduodenal ulcers associated with lumiracoxib compared with ibuprofen in patients with rheumatoid arthritis.
Kivitz AJ, Nayiager S, Schimansky T, Gimona A, Thurston HJ, Hawkey C. Kivitz AJ, et al. Aliment Pharmacol Ther. 2004 Jun 1;19(11):1189-98. doi: 10.1111/j.1365-2036.2004.01956.x. Aliment Pharmacol Ther. 2004. PMID: 15153172 Clinical Trial.
Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group.
Hawkey CJ, Karrasch JA, Szczepañski L, Walker DG, Barkun A, Swannell AJ, Yeomans ND. Hawkey CJ, et al. N Engl J Med. 1998 Mar 12;338(11):727-34. doi: 10.1056/NEJM199803123381105. N Engl J Med. 1998. PMID: 9494149 Clinical Trial.
A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versus Omeprazole for NSAID-associated Ulcer Treatment (ASTRONAUT) Study Group.
Yeomans ND, Tulassay Z, Juhász L, Rácz I, Howard JM, van Rensburg CJ, Swannell AJ, Hawkey CJ. Yeomans ND, et al. Among authors: hawkey cj. N Engl J Med. 1998 Mar 12;338(11):719-26. doi: 10.1056/NEJM199803123381104. N Engl J Med. 1998. PMID: 9494148 Clinical Trial.
Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugs.
Taha AS, Hudson N, Hawkey CJ, Swannell AJ, Trye PN, Cottrell J, Mann SG, Simon TJ, Sturrock RD, Russell RI. Taha AS, et al. Among authors: hawkey cj. N Engl J Med. 1996 May 30;334(22):1435-9. doi: 10.1056/NEJM199605303342204. N Engl J Med. 1996. PMID: 8618582 Clinical Trial.
Review article: the gastrointestinal safety profile of rofecoxib, a highly selective inhibitor of cyclooxygenase-2, in humans.
Hawkey CJ, Jackson L, Harper SE, Simon TJ, Mortensen E, Lines CR. Hawkey CJ, et al. Aliment Pharmacol Ther. 2001 Jan;15(1):1-9. doi: 10.1046/j.1365-2036.2001.00894.x. Aliment Pharmacol Ther. 2001. PMID: 11136272 Review.
Rofecoxib, a COX-2 inhibitor, does not inhibit human gastric mucosal prostaglandin production.
Wight NJ, Gottesdiener K, Garlick NM, Atherton CT, Novak S, Gertz BJ, Calder NA, Cote J, Wong P, Dallob A, Hawkey CJ. Wight NJ, et al. Among authors: hawkey cj. Gastroenterology. 2001 Mar;120(4):867-73. doi: 10.1053/gast.2001.22432. Gastroenterology. 2001. PMID: 11231941 Clinical Trial.
Dual COX inhibition and upper gastrointestinal damage.
Skelly MM, Hawkey CJ. Skelly MM, et al. Among authors: hawkey cj. Curr Pharm Des. 2003;9(27):2191-5. doi: 10.2174/1381612033453965. Curr Pharm Des. 2003. PMID: 14529399 Review.
COX-1 and COX-2 inhibitors.
Hawkey CJ. Hawkey CJ. Best Pract Res Clin Gastroenterol. 2001 Oct;15(5):801-20. doi: 10.1053/bega.2001.0236. Best Pract Res Clin Gastroenterol. 2001. PMID: 11566042 Review.
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