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AMP-activated protein kinase: the energy charge hypothesis revisited.
Hardie DG, Hawley SA. Hardie DG, et al. Among authors: hawley sa. Bioessays. 2001 Dec;23(12):1112-9. doi: 10.1002/bies.10009. Bioessays. 2001. PMID: 11746230 Review.
AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge.
Hardie DG, Salt IP, Hawley SA, Davies SP. Hardie DG, et al. Among authors: hawley sa. Biochem J. 1999 Mar 15;338 ( Pt 3)(Pt 3):717-22. Biochem J. 1999. PMID: 10051444 Free PMC article.
AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.
Salt I, Celler JW, Hawley SA, Prescott A, Woods A, Carling D, Hardie DG. Salt I, et al. Among authors: hawley sa. Biochem J. 1998 Aug 15;334 ( Pt 1)(Pt 1):177-87. doi: 10.1042/bj3340177. Biochem J. 1998. PMID: 9693118 Free PMC article.
Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio.
Wilson WA, Hawley SA, Hardie DG. Wilson WA, et al. Among authors: hawley sa. Curr Biol. 1996 Nov 1;6(11):1426-34. doi: 10.1016/s0960-9822(96)00747-6. Curr Biol. 1996. PMID: 8939604
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase.
Hawley SA, Davison M, Woods A, Davies SP, Beri RK, Carling D, Hardie DG. Hawley SA, et al. J Biol Chem. 1996 Nov 1;271(44):27879-87. doi: 10.1074/jbc.271.44.27879. J Biol Chem. 1996. PMID: 8910387
As well as suggesting a mechanism of activation of AMP-activated protein kinase, this finding is consistent with our recent report that the AMP-activated protein kinase kinase can slowly phosphorylate and activate calmodulin-dependent protein kinase I, at least in vitro (Hawle
As well as suggesting a mechanism of activation of AMP-activated protein kinase, this finding is consistent with our recent report that the …
Activation of rat liver AMP-activated protein kinase by kinase kinase in a purified, reconstituted system. Effects of AMP and AMP analogues.
Weekes J, Hawley SA, Corton J, Shugar D, Hardie DG. Weekes J, et al. Among authors: hawley sa. Eur J Biochem. 1994 Feb 1;219(3):751-7. doi: 10.1111/j.1432-1033.1994.tb18554.x. Eur J Biochem. 1994. PMID: 8112325
Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure.
Davies SP, Hawley SA, Woods A, Carling D, Haystead TA, Hardie DG. Davies SP, et al. Among authors: hawley sa. Eur J Biochem. 1994 Jul 15;223(2):351-7. doi: 10.1111/j.1432-1033.1994.tb19001.x. Eur J Biochem. 1994. PMID: 8055903
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
Corton JM, Gillespie JG, Hawley SA, Hardie DG. Corton JM, et al. Among authors: hawley sa. Eur J Biochem. 1995 Apr 15;229(2):558-65. doi: 10.1111/j.1432-1033.1995.tb20498.x. Eur J Biochem. 1995. PMID: 7744080
5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms.
Hawley SA, Selbert MA, Goldstein EG, Edelman AM, Carling D, Hardie DG. Hawley SA, et al. J Biol Chem. 1995 Nov 10;270(45):27186-91. doi: 10.1074/jbc.270.45.27186. J Biol Chem. 1995. PMID: 7592975
The AMP-activated protein kinase gene is highly expressed in rat skeletal muscle. Alternative splicing and tissue distribution of the mRNA.
Verhoeven AJ, Woods A, Brennan CH, Hawley SA, Hardie DG, Scott J, Beri RK, Carling D. Verhoeven AJ, et al. Among authors: hawley sa. Eur J Biochem. 1995 Mar 1;228(2):236-43. Eur J Biochem. 1995. PMID: 7705334
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