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Blockade of α2-adrenergic or metabotropic glutamate receptors induces glutamate release in the locus coeruleus to activate descending inhibition in rats with chronic neuropathic hypersensitivity.
Hayashida KI, Kimuram M, Eisenach JC. Hayashida KI, et al. Neurosci Lett. 2018 May 29;676:41-45. doi: 10.1016/j.neulet.2018.04.011. Epub 2018 Apr 5. Neurosci Lett. 2018. PMID: 29627342 Free PMC article.
Psychosocial Stress Delays Recovery of Postoperative Pain Following Incisional Surgery in the Rat.
Arora V, Martin TJ, Aschenbrenner CA, Hayashida K, Kim SA, Parker RA, Eisenach JC, Peters CM. Arora V, et al. Neuroscience. 2018 Jul 1;382:35-47. doi: 10.1016/j.neuroscience.2018.04.014. Epub 2018 Apr 22. Neuroscience. 2018. PMID: 29694918 Free PMC article.
Nerve injury induces a new profile of tactile and mechanical nociceptor input from undamaged peripheral afferents.
Boada MD, Gutierrez S, Aschenbrenner CA, Houle TT, Hayashida K, Ririe DG, Eisenach JC. Boada MD, et al. J Neurophysiol. 2015 Jan 1;113(1):100-9. doi: 10.1152/jn.00506.2014. Epub 2014 Oct 1. J Neurophysiol. 2015. PMID: 25274350 Free PMC article.
Antinociception induced by a novel α2A adrenergic receptor agonist in rodents acute and chronic pain models.
Sudo RT, do Amaral RV, Monteiro CEDS, Pitta IDR, Lima MDC, Montes GC, Ririe DG, Hayashida K, Zapata-Sudo G. Sudo RT, et al. Eur J Pharmacol. 2017 Nov 15;815:210-218. doi: 10.1016/j.ejphar.2017.09.018. Epub 2017 Sep 19. Eur J Pharmacol. 2017. PMID: 28935564
Down-regulation of astroglial glutamate transporter-1 in the locus coeruleus impairs pain-evoked endogenous analgesia in rats.
Kimura M, Suto T, Eisenach JC, Hayashida K. Kimura M, et al. Neurosci Lett. 2015 Nov 3;608:18-22. doi: 10.1016/j.neulet.2015.09.036. Epub 2015 Oct 9. Neurosci Lett. 2015. PMID: 26450532 Free PMC article.
Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes.
Yoshizumi M, Eisenach JC, Hayashida K. Yoshizumi M, et al. Eur J Pharmacol. 2012 Feb 29;677(1-3):87-92. doi: 10.1016/j.ejphar.2011.12.015. Epub 2011 Dec 21. Eur J Pharmacol. 2012. PMID: 22206816 Free PMC article.
Gabapentin inhibits γ-amino butyric acid release in the locus coeruleus but not in the spinal dorsal horn after peripheral nerve injury in rats.
Yoshizumi M, Parker RA, Eisenach JC, Hayashida K. Yoshizumi M, et al. Anesthesiology. 2012 Jun;116(6):1347-53. doi: 10.1097/ALN.0b013e318254e6fd. Anesthesiology. 2012. PMID: 22487864 Free PMC article.
Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury.
Severino AL, Chen R, Hayashida K, Aschenbrenner CA, Sun H, Peters CM, Gutierrez S, Pan B, Eisenach JC. Severino AL, et al. Anesthesiology. 2018 Sep;129(3):544-556. doi: 10.1097/ALN.0000000000002290. Anesthesiology. 2018. PMID: 29912007 Free PMC article.
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