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TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice.
Hamad SH, Montgomery SA, Simon JM, Bowman BM, Spainhower KB, Murphy RM, Knudsen ES, Fenton SE, Randell SH, Holt JR, Hayes DN, Witkiewicz AK, Oliver TG, Major MB, Weissman BE. Hamad SH, et al. Among authors: hayes dn. Oncogene. 2022 Jun;41(25):3423-3432. doi: 10.1038/s41388-022-02348-0. Epub 2022 May 16. Oncogene. 2022. PMID: 35577980 Free PMC article.
Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types.
Wilkerson MD, Yin X, Hoadley KA, Liu Y, Hayward MC, Cabanski CR, Muldrew K, Miller CR, Randell SH, Socinski MA, Parsons AM, Funkhouser WK, Lee CB, Roberts PJ, Thorne L, Bernard PS, Perou CM, Hayes DN. Wilkerson MD, et al. Among authors: hayes dn. Clin Cancer Res. 2010 Oct 1;16(19):4864-75. doi: 10.1158/1078-0432.CCR-10-0199. Epub 2010 Jul 19. Clin Cancer Res. 2010. PMID: 20643781 Free PMC article.
Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation.
Wilkerson MD, Yin X, Walter V, Zhao N, Cabanski CR, Hayward MC, Miller CR, Socinski MA, Parsons AM, Thorne LB, Haithcock BE, Veeramachaneni NK, Funkhouser WK, Randell SH, Bernard PS, Perou CM, Hayes DN. Wilkerson MD, et al. Among authors: hayes dn. PLoS One. 2012;7(5):e36530. doi: 10.1371/journal.pone.0036530. Epub 2012 May 10. PLoS One. 2012. PMID: 22590557 Free PMC article.
Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes.
Walter V, Yin X, Wilkerson MD, Cabanski CR, Zhao N, Du Y, Ang MK, Hayward MC, Salazar AH, Hoadley KA, Fritchie K, Sailey CJ, Weissler MC, Shockley WW, Zanation AM, Hackman T, Thorne LB, Funkhouser WD, Muldrew KL, Olshan AF, Randell SH, Wright FA, Shores CG, Hayes DN. Walter V, et al. Among authors: hayes dn. PLoS One. 2013;8(2):e56823. doi: 10.1371/journal.pone.0056823. Epub 2013 Feb 22. PLoS One. 2013. PMID: 23451093 Free PMC article.
Gene silencing associated with SWI/SNF complex loss during NSCLC development.
Song S, Walter V, Karaca M, Li Y, Bartlett CS, Smiraglia DJ, Serber D, Sproul CD, Plass C, Zhang J, Hayes DN, Zheng Y, Weissman BE. Song S, et al. Among authors: hayes dn. Mol Cancer Res. 2014 Apr;12(4):560-70. doi: 10.1158/1541-7786.MCR-13-0427. Epub 2014 Jan 20. Mol Cancer Res. 2014. PMID: 24445599 Free PMC article.
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss.
Gross AM, Orosco RK, Shen JP, Egloff AM, Carter H, Hofree M, Choueiri M, Coffey CS, Lippman SM, Hayes DN, Cohen EE, Grandis JR, Nguyen QT, Ideker T. Gross AM, et al. Among authors: hayes dn. Nat Genet. 2014 Sep;46(9):939-43. doi: 10.1038/ng.3051. Epub 2014 Aug 3. Nat Genet. 2014. PMID: 25086664 Free PMC article.
Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking.
Porrello A, Leslie PL, Harrison EB, Gorentla BK, Kattula S, Ghosh SK, Azam SH, Holtzhausen A, Chao YL, Hayward MC, Waugh TA, Bae S, Godfrey V, Randell SH, Oderup C, Makowski L, Weiss J, Wilkerson MD, Hayes DN, Earp HS, Baldwin AS, Wolberg AS, Pecot CV. Porrello A, et al. Among authors: hayes dn. Nat Commun. 2018 May 18;9(1):1988. doi: 10.1038/s41467-018-04355-w. Nat Commun. 2018. PMID: 29777108 Free PMC article.
298 results