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The K5 capsule of Escherichia coli strain Nissle 1917 is important in stimulating expression of Toll-like receptor 5, CD14, MyD88, and TRIF together with the induction of interleukin-8 expression via the mitogen-activated protein kinase pathway in epithelial cells.
Hafez M, Hayes K, Goldrick M, Grencis RK, Roberts IS. Hafez M, et al. Infect Immun. 2010 May;78(5):2153-62. doi: 10.1128/IAI.01406-09. Epub 2010 Feb 9. Infect Immun. 2010. PMID: 20145095 Free PMC article.
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