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66 results
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Mitochondrial protein quality control during biogenesis and aging.
Baker BM, Haynes CM. Baker BM, et al. Among authors: haynes cm. Trends Biochem Sci. 2011 May;36(5):254-61. doi: 10.1016/j.tibs.2011.01.004. Epub 2011 Feb 25. Trends Biochem Sci. 2011. PMID: 21353780 Review.
Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death.
Haynes CM, Titus EA, Cooper AA. Haynes CM, et al. Mol Cell. 2004 Sep 10;15(5):767-76. doi: 10.1016/j.molcel.2004.08.025. Mol Cell. 2004. PMID: 15350220
Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response.
Benedetti C, Haynes CM, Yang Y, Harding HP, Ron D. Benedetti C, et al. Among authors: haynes cm. Genetics. 2006 Sep;174(1):229-39. doi: 10.1534/genetics.106.061580. Epub 2006 Jul 2. Genetics. 2006. PMID: 16816413 Free PMC article.
ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans.
Haynes CM, Petrova K, Benedetti C, Yang Y, Ron D. Haynes CM, et al. Dev Cell. 2007 Oct;13(4):467-80. doi: 10.1016/j.devcel.2007.07.016. Dev Cell. 2007. PMID: 17925224
The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans.
Haynes CM, Yang Y, Blais SP, Neubert TA, Ron D. Haynes CM, et al. Mol Cell. 2010 Feb 26;37(4):529-40. doi: 10.1016/j.molcel.2010.01.015. Mol Cell. 2010. PMID: 20188671 Free PMC article.
The mitochondrial UPR - protecting organelle protein homeostasis.
Haynes CM, Ron D. Haynes CM, et al. J Cell Sci. 2010 Nov 15;123(Pt 22):3849-55. doi: 10.1242/jcs.075119. J Cell Sci. 2010. PMID: 21048161 Review.
Signaling the mitochondrial unfolded protein response.
Pellegrino MW, Nargund AM, Haynes CM. Pellegrino MW, et al. Among authors: haynes cm. Biochim Biophys Acta. 2013 Feb;1833(2):410-6. doi: 10.1016/j.bbamcr.2012.02.019. Epub 2012 Mar 14. Biochim Biophys Acta. 2013. PMID: 22445420 Free PMC article. Review.
Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.
Nargund AM, Pellegrino MW, Fiorese CJ, Baker BM, Haynes CM. Nargund AM, et al. Among authors: haynes cm. Science. 2012 Aug 3;337(6094):587-90. doi: 10.1126/science.1223560. Epub 2012 Jun 14. Science. 2012. PMID: 22700657 Free PMC article.
Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2.
Baker BM, Nargund AM, Sun T, Haynes CM. Baker BM, et al. Among authors: haynes cm. PLoS Genet. 2012;8(6):e1002760. doi: 10.1371/journal.pgen.1002760. Epub 2012 Jun 14. PLoS Genet. 2012. PMID: 22719267 Free PMC article.
Physiological consequences of complex II inhibition for aging, disease, and the mKATP channel.
Wojtovich AP, Smith CO, Haynes CM, Nehrke KW, Brookes PS. Wojtovich AP, et al. Among authors: haynes cm. Biochim Biophys Acta. 2013 May;1827(5):598-611. doi: 10.1016/j.bbabio.2012.12.007. Epub 2013 Jan 2. Biochim Biophys Acta. 2013. PMID: 23291191 Free PMC article. Review.
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