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A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2-3)Gal- sequences of glycophorin A.
Orlandi PA, Klotz FW, Haynes JD. Orlandi PA, et al. Among authors: haynes jd. J Cell Biol. 1992 Feb;116(4):901-9. doi: 10.1083/jcb.116.4.901. J Cell Biol. 1992. PMID: 1310320 Free PMC article.
Alanine mutagenesis of the primary antigenic escape residue cluster, c1, of apical membrane antigen 1.
Dutta S, Dlugosz LS, Clayton JW, Pool CD, Haynes JD, Gasser RA 3rd, Batchelor AH. Dutta S, et al. Among authors: haynes jd. Infect Immun. 2010 Feb;78(2):661-71. doi: 10.1128/IAI.00866-09. Epub 2009 Nov 30. Infect Immun. 2010. PMID: 19948834 Free PMC article.
High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model.
Dutta S, Sullivan JS, Grady KK, Haynes JD, Komisar J, Batchelor AH, Soisson L, Diggs CL, Heppner DG, Lanar DE, Collins WE, Barnwell JW. Dutta S, et al. Among authors: haynes jd. PLoS One. 2009 Dec 3;4(12):e8138. doi: 10.1371/journal.pone.0008138. PLoS One. 2009. PMID: 19997632 Free PMC article.
Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.
Dutta S, Dlugosz LS, Drew DR, Ge X, Ababacar D, Rovira YI, Moch JK, Shi M, Long CA, Foley M, Beeson JG, Anders RF, Miura K, Haynes JD, Batchelor AH. Dutta S, et al. Among authors: haynes jd. PLoS Pathog. 2013;9(12):e1003840. doi: 10.1371/journal.ppat.1003840. Epub 2013 Dec 26. PLoS Pathog. 2013. PMID: 24385910 Free PMC article.
Plasmodium falciparum field isolates use complement receptor 1 (CR1) as a receptor for invasion of erythrocytes.
Awandare GA, Spadafora C, Moch JK, Dutta S, Haynes JD, Stoute JA. Awandare GA, et al. Among authors: haynes jd. Mol Biochem Parasitol. 2011 May;177(1):57-60. doi: 10.1016/j.molbiopara.2011.01.005. Epub 2011 Jan 18. Mol Biochem Parasitol. 2011. PMID: 21251929 Free PMC article.
Automated synchronization of Plasmodium falciparum parasites by culture in a temperature-cycling incubator.
Haynes JD, Moch JK. Haynes JD, et al. Methods Mol Med. 2002;72:489-97. doi: 10.1385/1-59259-271-6:489. Methods Mol Med. 2002. PMID: 12125145 No abstract available.
Erythrocytic malaria growth or invasion inhibition assays with emphasis on suspension culture GIA.
Haynes JD, Moch JK, Smoot DS. Haynes JD, et al. Methods Mol Med. 2002;72:535-54. doi: 10.1385/1-59259-271-6:535. Methods Mol Med. 2002. PMID: 12125152
Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach.
Kumar K, Srinivasan P, Nold MJ, Moch JK, Reiter K, Sturdevant D, Otto TD, Squires RB, Herrera R, Nagarajan V, Rayner JC, Porcella SF, Geromanos SJ, Haynes JD, Narum DL. Kumar K, et al. Among authors: haynes jd. Sci Rep. 2017 Dec 7;7(1):17146. doi: 10.1038/s41598-017-17505-9. Sci Rep. 2017. PMID: 29215067 Free PMC article.
Mode of action of invasion-inhibitory antibodies directed against apical membrane antigen 1 of Plasmodium falciparum.
Dutta S, Haynes JD, Barbosa A, Ware LA, Snavely JD, Moch JK, Thomas AW, Lanar DE. Dutta S, et al. Among authors: haynes jd. Infect Immun. 2005 Apr;73(4):2116-22. doi: 10.1128/IAI.73.4.2116-2122.2005. Infect Immun. 2005. PMID: 15784553 Free PMC article.
Production of the subdomains of the Plasmodium falciparum apical membrane antigen 1 ectodomain and analysis of the immune response.
Lalitha PV, Ware LA, Barbosa A, Dutta S, Moch JK, Haynes JD, Fileta BB, White CE, Lanar DE. Lalitha PV, et al. Among authors: haynes jd. Infect Immun. 2004 Aug;72(8):4464-70. doi: 10.1128/IAI.72.8.4464-4470.2004. Infect Immun. 2004. PMID: 15271904 Free PMC article.
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