Haynes MK - Search Results

1

Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.

Haynes MK, Strouse JJ, Waller A, Leitao A, Curpan RF, Bologa C, Oprea TI, Prossnitz ER, Edwards BS, Sklar LA, Thompson TA. Haynes MK, et al. J Biomol Screen. 2009 Jul;14(6):596-609. doi: 10.1177/1087057109335671. Epub 2009 May 21. J Biomol Screen. 2009. PMID: 19470718 Free PMC article.

2

Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.

Chigaev A, Smagley Y, Zhang Y, Waller A, Haynes MK, Amit O, Wang W, Larson RS, Sklar LA. Chigaev A, et al. Among authors: haynes mk. J Biol Chem. 2011 Jun 10;286(23):20375-86. doi: 10.1074/jbc.M110.206185. Epub 2011 Apr 22. J Biol Chem. 2011. PMID: 21515675 Free PMC article.

3

Drug Repurposing from an Academic Perspective.

Oprea TI, Bauman JE, Bologa CG, Buranda T, Chigaev A, Edwards BS, Jarvik JW, Gresham HD, Haynes MK, Hjelle B, Hromas R, Hudson L, Mackenzie DA, Muller CY, Reed JC, Simons PC, Smagley Y, Strouse J, Surviladze Z, Thompson T, Ursu O, Waller A, Wandinger-Ness A, Winter SS, Wu Y, Young SM, Larson RS, Willman C, Sklar LA. Oprea TI, et al. Among authors: haynes mk. Drug Discov Today Ther Strateg. 2011 Winter;8(3-4):61-69. doi: 10.1016/j.ddstr.2011.10.002. Drug Discov Today Ther Strateg. 2011. PMID: 22368688 Free PMC article.

4

A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6.

Polireddy K, Khan MM, Chavan H, Young S, Ma X, Waller A, Garcia M, Perez D, Chavez S, Strouse JJ, Haynes MK, Bologa CG, Oprea TI, Tegos GP, Sklar LA, Krishnamurthy P. Polireddy K, et al. Among authors: haynes mk. PLoS One. 2012;7(7):e40005. doi: 10.1371/journal.pone.0040005. Epub 2012 Jul 10. PLoS One. 2012. PMID: 22808084 Free PMC article.

5

Flow cytometry enables a high-throughput homogeneous fluorescent antibody-binding assay for cytotoxic T cell lytic granule exocytosis.

Florian AE, Lepensky CK, Kwon O, Haynes MK, Sklar LA, Zweifach A. Florian AE, et al. Among authors: haynes mk. J Biomol Screen. 2013 Apr;18(4):420-9. doi: 10.1177/1087057112466697. Epub 2012 Nov 15. J Biomol Screen. 2013. PMID: 23160568 Free PMC article.

6

Small Molecule Inhibitors Limit Endothelial Cell Invasion by Staphylococcus aureus.

Cordero D, Fullenkamp CR, Pelly RR, Reed KM, Caffo LM, Zahrt AN, Newman M, Komanapalli S, Niemeier EM, Bishop DL, Bruns HA, Haynes MK, Sklar LA, Sammelson RE, McDowell SA. Cordero D, et al. Among authors: haynes mk. Curr Pharm Biotechnol. 2014;15(8):727-37. doi: 10.2174/1389201015666140909124310. Curr Pharm Biotechnol. 2014. PMID: 25213310 Free PMC article.

7

FRET detection of lymphocyte function-associated antigen-1 conformational extension.

Chigaev A, Smagley Y, Haynes MK, Ursu O, Bologa CG, Halip L, Oprea T, Waller A, Carter MB, Zhang Y, Wang W, Buranda T, Sklar LA. Chigaev A, et al. Among authors: haynes mk. Mol Biol Cell. 2015 Jan 1;26(1):43-54. doi: 10.1091/mbc.E14-06-1050. Epub 2014 Nov 5. Mol Biol Cell. 2015. PMID: 25378583 Free PMC article.

8

A high-throughput phenotypic screen of cytotoxic T lymphocyte lytic granule exocytosis reveals candidate immunosuppressants.

Zhao Z, Haynes MK, Ursu O, Edwards BS, Sklar LA, Zweifach A. Zhao Z, et al. Among authors: haynes mk. J Biomol Screen. 2015 Mar;20(3):359-71. doi: 10.1177/1087057114557620. Epub 2014 Nov 7. J Biomol Screen. 2015. PMID: 25381253 Free PMC article.

9

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, Eheim AL, Stoeckigt D, Maxcy KL, Cobert JM, Bachand J, Szekely BA, Mukherjee S, Sklar LA, Kotz JD, Clish CB, Sadreyev RI, Clemons PA, Janzer A, Schreiber SL, Scadden DT. Sykes DB, et al. Among authors: haynes mk. Cell. 2016 Sep 22;167(1):171-186.e15. doi: 10.1016/j.cell.2016.08.057. Epub 2016 Sep 15. Cell. 2016. PMID: 27641501 Free PMC article.

10

High-Throughput Flow Cytometry Screening of Multidrug Efflux Systems.

Haynes MK, Garcia M, Peters R, Waller A, Tedesco P, Ursu O, Bologa CG, Santos RG, Pinilla C, Wu TH, Lovchik JA, Oprea TI, Sklar LA, Tegos GP. Haynes MK, et al. Methods Mol Biol. 2018;1700:293-318. doi: 10.1007/978-1-4939-7454-2_16. Methods Mol Biol. 2018. PMID: 29177837

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