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Hb Tacoma by seven HbA1c methods - one with significant interference.
Mäenpää A, Kangastie M, Kangastupa P. Mäenpää A, et al. Scand J Clin Lab Invest. 2024 Nov-Dec;84(7-8):447-451. doi: 10.1080/00365513.2024.2417383. Epub 2024 Oct 27. Scand J Clin Lab Invest. 2024. PMID: 39462895 Free article.
Hemoglobin Tacoma is known to potentially interfere HbA1c assays. The variant is common in Finland with prevalence of up to 2% regionally and cases are also reported in areas that have attracted Finnish immigrants, especially in Sweden and North America. ...T
Hemoglobin Tacoma is known to potentially interfere HbA1c assays. The variant is common in Finland with prevalence of u
The interference by HbF on HbA1c (BM Test HbA1c) measurement in enzymatic method.
Nitta T, Yamashiro Y, Hattori Y, Ezumi T, Nishioka M, Nakamura J. Nitta T, et al. Ann Clin Biochem. 2015 Sep;52(Pt 5):569-75. doi: 10.1177/0004563214568872. Epub 2015 Jan 13. Ann Clin Biochem. 2015. PMID: 25587198
In this report, we discuss the effect of HbF on the HbA1c measurement by the enzymatic method (BM Test HbA1c) which can be applied to automatic analyzer of high sample throughput. ...BM Test HbA1c had some deviation from the International Federation of Clinic …
In this report, we discuss the effect of HbF on the HbA1c measurement by the enzymatic method (BM Test HbA1c) which can be app …
Analytical interference of 33 different hemoglobin variants on HbA1c measurements comparing high-performance liquid chromatography with whole blood enzymatic assay: A multi-center study.
Zechmeister B, Erden T, Kreutzig B, Weber M, Joly P, Erdmann J, Brockmann-Hönig C, Fischer A, Eidizadeh A. Zechmeister B, et al. Clin Chim Acta. 2022 Jun 1;531:145-151. doi: 10.1016/j.cca.2022.03.028. Epub 2022 Apr 1. Clin Chim Acta. 2022. PMID: 35378091
BACKGROUND AND AIMS: The concentration of glycated hemoglobin (HbA1c) is an essential diagnostic and therapeutic biomarker in diabetes mellitus. However, it is known that Hb structural variants and synthesis disorders, can affect the HbA1c measurement …
BACKGROUND AND AIMS: The concentration of glycated hemoglobin (HbA1c) is an essential diagnostic and therapeutic biomar …
HbA1c Below the Reportable Range.
Pant V. Pant V. Lab Med. 2022 Mar 7;53(2):e44-e47. doi: 10.1093/labmed/lmab082. Lab Med. 2022. PMID: 34611711 Free article.
This case report concerns a 71 year old female patient who had a very low glycosylated hemoglobin (HbA1c) despite having a high level of fasting blood glucose. The patient had a decreased erythrocyte count, elevated red blood cell indices, and a reticulocyte count w …
This case report concerns a 71 year old female patient who had a very low glycosylated hemoglobin (HbA1c) despite having a hig …
Interference of common haemoglobin variants with the Tosoh G7 standard mode HbA1c method.
Piehler AP, Grimholt RM, Bjerner J, Buchmann MS. Piehler AP, et al. Scand J Clin Lab Invest. 2015 Sep;75(5):362-6. doi: 10.3109/00365513.2015.1031687. Epub 2015 Apr 10. Scand J Clin Lab Invest. 2015. PMID: 25858015
BACKGROUND: HbA1c methods may be prone to interference by the presence of haemoglobin variants. In contrast to the variant mode of the HbA1c method on the Tosoh G7 instrument, the literature lacks investigations of haemoglobin variant interference with …
BACKGROUND: HbA1c methods may be prone to interference by the presence of haemoglobin variants. In contrast to the variant mod …
The Sickle Effect: The Silent Titan Affecting Glycated Hemoglobin Reliability.
Gordon DK, Hussain M, Kumar P, Khan S, Khan S. Gordon DK, et al. Cureus. 2020 Aug 12;12(8):e9685. doi: 10.7759/cureus.9685. Cureus. 2020. PMID: 32923278 Free PMC article. Review.
Hemoglobin A1c (HbA1c) is a popular invaluable tool in the diagnosis of Type 2 diabetes for red blood cells (RBCs) with a lifespan of 120 days; however, many factors, including hemoglobinopathies, affect its accuracy. ...The National Glycohemoglobin Standardi
Hemoglobin A1c (HbA1c) is a popular invaluable tool in the diagnosis of Type 2 diabetes for red blood cells (RBCs) with a life
Glycated albumin: a potential biomarker in diabetes.
Freitas PAC, Ehlert LR, Camargo JL. Freitas PAC, et al. Arch Endocrinol Metab. 2017 May-Jun;61(3):296-304. doi: 10.1590/2359-3997000000272. Arch Endocrinol Metab. 2017. PMID: 28699985 Free PMC article. Review.
Diabetes mellitus (DM) is a chronic and metabolic disease that presents a high global incidence. Glycated hemoglobin (A1C) is the reference test for long-term glucose monitoring, and it exhibits an association with diabetic chronic complications. However, A1C is not …
Diabetes mellitus (DM) is a chronic and metabolic disease that presents a high global incidence. Glycated hemoglobin (A1C) is …
Pathology consultation on HbA(1c) methods and interferences.
Rhea JM, Molinaro R. Rhea JM, et al. Am J Clin Pathol. 2014 Jan;141(1):5-16. doi: 10.1309/AJCPQ23GTTMLAEVL. Am J Clin Pathol. 2014. PMID: 24343732 Review.
OBJECTIVES: To review the various hemoglobin (Hb) A1c methods, with a focus on interferences resulting from Hb variants. METHODS: HbA1c is a marker used for the diagnosis and management of diabetes. Each available HbA1c method has advantages and challe …
OBJECTIVES: To review the various hemoglobin (Hb) A1c methods, with a focus on interferences resulting from Hb variants. METHO …
Falsely elevated hemoglobin A1c due to S-beta+-thalassemia interference in Bio-Rad Variant II Turbo HbA1c assay.
Zhu Y, Williams LM. Zhu Y, et al. Clin Chim Acta. 2009 Nov;409(1-2):18-20. doi: 10.1016/j.cca.2009.08.009. Epub 2009 Aug 19. Clin Chim Acta. 2009. PMID: 19698705
BACKGROUND: Hemoglobin (Hb) S-beta(+)-thalassemia is a relatively mild form of S-beta-thalassemia, but it may interfere with HbA1c (A1c) assay. ...The former measured the A1c fraction only of glycated HbA, while the latter measured all Hb variants that …
BACKGROUND: Hemoglobin (Hb) S-beta(+)-thalassemia is a relatively mild form of S-beta-thalassemia, but it may interfere with …
A Hemoglobinopathy That Produces an Array of Different Hemoglobin A1c Values.
Marin MJ, Osa-Andrews B, Maher PA, Wasserfall C, Winter WE, Muzwagi AB, Harris NS. Marin MJ, et al. J Hematol. 2024 Jun;13(3):99-103. doi: 10.14740/jh1268. Epub 2024 Jun 28. J Hematol. 2024. PMID: 38993739 Free PMC article.
Hemoglobin A1c (HbA1c) refers to non-enzymatically glycated hemoglobin and reflects the patient's glycemic status over approximately 3 months. ...Occasionally however, rare and mostly benign hemoglobinopathies can interfere with this tech
Hemoglobin A1c (HbA1c) refers to non-enzymatically glycated hemoglobin and reflects the patient's glycemic statu
85 results