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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1985 1
1990 1
1993 2
2001 1
2003 1
2006 1
2007 1
2009 1
2010 1
2012 1
2013 1
2014 1
2016 1
2024 0

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15 results

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Page 1
Malaria parasites and red cell variants: when a house is not a home.
Taylor SM, Fairhurst RM. Taylor SM, et al. Curr Opin Hematol. 2014 May;21(3):193-200. doi: 10.1097/MOH.0000000000000039. Curr Opin Hematol. 2014. PMID: 24675047 Free PMC article. Review.
RECENT FINDINGS: New red cell variants, including an innate variant in the red cell's major Ca2+ pump and the acquired state of iron deficiency, have been associated with protection from clinical falciparum malaria. The polymorphisms hemoglobin C (HbC) and hemogl
RECENT FINDINGS: New red cell variants, including an innate variant in the red cell's major Ca2+ pump and the acquired state of iron deficie …
Hemoglobinopathies: slicing the Gordian knot of Plasmodium falciparum malaria pathogenesis.
Taylor SM, Cerami C, Fairhurst RM. Taylor SM, et al. PLoS Pathog. 2013;9(5):e1003327. doi: 10.1371/journal.ppat.1003327. Epub 2013 May 16. PLoS Pathog. 2013. PMID: 23696730 Free PMC article. Review.
Owing to the co-evolution of humans and P. falciparum parasites, the human genome is imprinted with polymorphisms that not only confer innate resistance to falciparum malaria, but also cause hemoglobinopathies. These genetic traits--including hemoglobin S (HbS), …
Owing to the co-evolution of humans and P. falciparum parasites, the human genome is imprinted with polymorphisms that not only confer innat …
Chronic Pulmonary Complications of Sickle Cell Disease.
Mehari A, Klings ES. Mehari A, et al. Chest. 2016 May;149(5):1313-24. doi: 10.1016/j.chest.2015.11.016. Epub 2016 Jan 13. Chest. 2016. PMID: 26836905 Free PMC article. Review.
In the United States, SCD affects approximately 100,000 individuals, most of African descent. Hemoglobin S (HbS) results from a glutamate-to-valine mutation of the sixth codon of the beta-hemoglobin allele; the homozygous genotype (HbSS) is associated with th …
In the United States, SCD affects approximately 100,000 individuals, most of African descent. Hemoglobin S (HbS) results from …
Mechanisms of genetically-based resistance to malaria.
López C, Saravia C, Gomez A, Hoebeke J, Patarroyo MA. López C, et al. Gene. 2010 Nov 1;467(1-2):1-12. doi: 10.1016/j.gene.2010.07.008. Epub 2010 Jul 22. Gene. 2010. PMID: 20655368 Review.
Some of the mechanisms underlying protection against this disease are described in this review for hemoglobin-inherited disorders (thalassemia, sickle-cell trait, HbC and HbE), erythrocyte polymorphisms (ovalocytosis and Duffy blood group), enzymopathies (G6PD defic …
Some of the mechanisms underlying protection against this disease are described in this review for hemoglobin-inherited disorders (th …
The population genetics of the haemoglobinopathies.
Flint J, Harding RM, Boyce AJ, Clegg JB. Flint J, et al. Baillieres Clin Haematol. 1993 Mar;6(1):215-62. doi: 10.1016/s0950-3536(05)80071-x. Baillieres Clin Haematol. 1993. PMID: 8353314 Review.
The haemoglobinopathies are the commonest single gene disorders known, and are so common in some regions of the world that the majority of the population carries at least one genetic abnormality affecting the structure or synthesis of the haemoglobin molecule. The prevalen …
The haemoglobinopathies are the commonest single gene disorders known, and are so common in some regions of the world that the majority of t …
The paradox of hemoglobin SC disease.
Nagel RL, Fabry ME, Steinberg MH. Nagel RL, et al. Blood Rev. 2003 Sep;17(3):167-78. doi: 10.1016/s0268-960x(03)00003-1. Blood Rev. 2003. PMID: 12818227 Review.
Homozygous HbC gene results only in mild hemolytic anemia. In HbSC disease red cells contain equal levels of HbS and HbC. ...This situation offers a unique opportunity: if we could inhibit the effect of HbC on K(+) transport we can cure the disease....
Homozygous HbC gene results only in mild hemolytic anemia. In HbSC disease red cells contain equal levels of HbS and HbC. ...T …
A review of variant hemoglobins interfering with hemoglobin A1c measurement.
Little RR, Roberts WL. Little RR, et al. J Diabetes Sci Technol. 2009 May 1;3(3):446-51. doi: 10.1177/193229680900300307. J Diabetes Sci Technol. 2009. PMID: 20144281 Free PMC article. Review.
The accuracy of HbA1c methods can be affected adversely by the presence of hemoglobin (Hb) variants or elevated levels of fetal hemoglobin (HbF). ...HbF is the major hemoglobin during intrauterine life; by the end of the first year, HbF falls to values close …
The accuracy of HbA1c methods can be affected adversely by the presence of hemoglobin (Hb) variants or elevated levels of fetal he
Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin.
Bry L, Chen PC, Sacks DB. Bry L, et al. Clin Chem. 2001 Feb;47(2):153-63. Clin Chem. 2001. PMID: 11159762 Review.
BACKGROUND: Glycohemoglobin (gHb), measured as hemoglobin (Hb) A(1c) or as total gHb, provides a common means for assessing long-term glycemic control in individuals with diabetes mellitus. ...We specifically address effects of commonly encountered Hbs, such as carbamyl-Hb …
BACKGROUND: Glycohemoglobin (gHb), measured as hemoglobin (Hb) A(1c) or as total gHb, provides a common means for assessing long-term …
An update on electrophoretic and chromatographic methods in the diagnosis of hemoglobinopathies.
Basset P, Braconnier F, Rosa J. Basset P, et al. J Chromatogr. 1982 Feb 12;227(2):267-304. doi: 10.1016/s0378-4347(00)80384-9. J Chromatogr. 1982. PMID: 7037806 Review.
This review primarily deals with methods for separations of hemoglobins. An introduction considers electrophoretic methods as well as those involving isoelectric focusing and chromatography. ...This update ends with a chapter on the interest of the assay of hemoglobins
This review primarily deals with methods for separations of hemoglobins. An introduction considers electrophoretic methods as well as …
Abnormal PfEMP1/knob display on Plasmodium falciparum-infected erythrocytes containing hemoglobin variants: fresh insights into malaria pathogenesis and protection.
Fairhurst RM, Bess CD, Krause MA. Fairhurst RM, et al. Microbes Infect. 2012 Aug;14(10):851-62. doi: 10.1016/j.micinf.2012.05.006. Epub 2012 May 23. Microbes Infect. 2012. PMID: 22634344 Free PMC article. Review.
Hemoglobin (Hb) variants are associated with reduced risk of life-threatening Plasmodium falciparum malaria syndromes, including cerebral malaria and severe malarial anemia. Despite decades of research, the mechanisms by which common Hb variants - sickle HbS, HbC, a
Hemoglobin (Hb) variants are associated with reduced risk of life-threatening Plasmodium falciparum malaria syndromes, including cere
15 results