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The signaling adaptors and pathways activated by TNF superfamily.
Dempsey PW, Doyle SE, He JQ, Cheng G. Dempsey PW, et al. Among authors: he jq. Cytokine Growth Factor Rev. 2003 Jun-Aug;14(3-4):193-209. doi: 10.1016/s1359-6101(03)00021-2. Cytokine Growth Factor Rev. 2003. PMID: 12787559 Review.
Control of canonical NF-kappaB activation through the NIK-IKK complex pathway.
Zarnegar B, Yamazaki S, He JQ, Cheng G. Zarnegar B, et al. Among authors: he jq. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3503-8. doi: 10.1073/pnas.0707959105. Epub 2008 Feb 21. Proc Natl Acad Sci U S A. 2008. PMID: 18292232 Free PMC article.
TRAF3 and its biological function.
He JQ, Oganesyan G, Saha SK, Zarnegar B, Cheng G. He JQ, et al. Adv Exp Med Biol. 2007;597:48-59. doi: 10.1007/978-0-387-70630-6_4. Adv Exp Med Biol. 2007. PMID: 17633016 Review.
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway.
He JQ, Saha SK, Kang JR, Zarnegar B, Cheng G. He JQ, et al. J Biol Chem. 2007 Feb 9;282(6):3688-94. doi: 10.1074/jbc.M610271200. Epub 2006 Dec 11. J Biol Chem. 2007. PMID: 17158868
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency.
He JQ, Zarnegar B, Oganesyan G, Saha SK, Yamazaki S, Doyle SE, Dempsey PW, Cheng G. He JQ, et al. J Exp Med. 2006 Oct 30;203(11):2413-8. doi: 10.1084/jem.20061166. Epub 2006 Oct 2. J Exp Med. 2006. PMID: 17015635 Free PMC article.
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif.
Saha SK, Pietras EM, He JQ, Kang JR, Liu SY, Oganesyan G, Shahangian A, Zarnegar B, Shiba TL, Wang Y, Cheng G. Saha SK, et al. Among authors: he jq. EMBO J. 2006 Jul 26;25(14):3257-63. doi: 10.1038/sj.emboj.7601220. Epub 2006 Jul 6. EMBO J. 2006. PMID: 16858409 Free PMC article.
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response.
Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, Zarnegar B, Perry A, Cheng G. Oganesyan G, et al. Among authors: he jq. Nature. 2006 Jan 12;439(7073):208-11. doi: 10.1038/nature04374. Epub 2005 Nov 23. Nature. 2006. PMID: 16306936
Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways.
Zarnegar B, He JQ, Oganesyan G, Hoffmann A, Baltimore D, Cheng G. Zarnegar B, et al. Among authors: he jq. Proc Natl Acad Sci U S A. 2004 May 25;101(21):8108-13. doi: 10.1073/pnas.0402629101. Epub 2004 May 17. Proc Natl Acad Sci U S A. 2004. PMID: 15148378 Free PMC article.
Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Li C, Ni CZ, Havert ML, Cabezas E, He J, Kaiser D, Reed JC, Satterthwait AC, Cheng G, Ely KR. Li C, et al. Structure. 2002 Mar;10(3):403-11. doi: 10.1016/s0969-2126(02)00733-5. Structure. 2002. PMID: 12005438
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.
Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh WC, Mak TW, Korneluk RG, Cheng G. Zarnegar BJ, et al. Nat Immunol. 2008 Dec;9(12):1371-8. doi: 10.1038/ni.1676. Epub 2008 Nov 9. Nat Immunol. 2008. PMID: 18997794 Free PMC article.
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