He Y - Search Results

1

Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice.

De Souza AT, Dai X, Spencer AG, Reppen T, Menzie A, Roesch PL, He Y, Caguyong MJ, Bloomer S, Herweijer H, Wolff JA, Hagstrom JE, Lewis DL, Linsley PS, Ulrich RG. De Souza AT, et al. Among authors: he y. Nucleic Acids Res. 2006;34(16):4486-94. doi: 10.1093/nar/gkl609. Epub 2006 Aug 31. Nucleic Acids Res. 2006. PMID: 16945951 Free PMC article.

2

PPARalpha siRNA-treated expression profiles uncover the causal sufficiency network for compound-induced liver hypertrophy.

Dai X, De Souza AT, Dai H, Lewis DL, Lee CK, Spencer AG, Herweijer H, Hagstrom JE, Linsley PS, Bassett DE, Ulrich RG, He YD. Dai X, et al. PLoS Comput Biol. 2007 Mar 2;3(3):e30. doi: 10.1371/journal.pcbi.0030030. Epub 2007 Jan 2. PLoS Comput Biol. 2007. PMID: 17335344 Free PMC article.

3

Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.

Slatter JG, Cheng O, Cornwell PD, de Souza A, Rockett J, Rushmore T, Hartley D, Evers R, He Y, Dai X, Hu R, Caguyong M, Roberts CJ, Castle J, Ulrich RG. Slatter JG, et al. Among authors: he y. Xenobiotica. 2006 Oct-Nov;36(10-11):902-37. doi: 10.1080/00498250600861694. Xenobiotica. 2006. PMID: 17118914

4

Compendium of gene expression profiles comprising a baseline model of the human liver drug metabolism transcriptome.

Slatter JG, Templeton IE, Castle JC, Kulkarni A, Rushmore TH, Richards K, He Y, Dai X, Cheng OJ, Caguyong M, Ulrich RG. Slatter JG, et al. Among authors: he y. Xenobiotica. 2006 Oct-Nov;36(10-11):938-62. doi: 10.1080/00498250600861728. Xenobiotica. 2006. PMID: 17118915

5

Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducers.

Coe KJ, Nelson SD, Ulrich RG, He Y, Dai X, Cheng O, Caguyong M, Roberts CJ, Slatter JG. Coe KJ, et al. Among authors: he y. Drug Metab Dispos. 2006 Jul;34(7):1266-75. doi: 10.1124/dmd.105.009159. Epub 2006 Apr 12. Drug Metab Dispos. 2006. PMID: 16611858

6

Development of an approach for ab initio estimation of compound-induced liver injury based on global gene transcriptional profiles.

Dai X, He YD, Dai H, Lum PY, Roberts CJ, Waring JF, Ulrich RG. Dai X, et al. Among authors: he yd. Genome Inform. 2006;17(2):77-88. Genome Inform. 2006. PMID: 17503381

7

Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia.

Lum PY, He YD, Slatter JG, Waring JF, Zelinsky N, Cavet G, Dai X, Fong O, Gum R, Jin L, Adamson GE, Roberts CJ, Olsen DB, Hazuda DJ, Ulrich RG. Lum PY, et al. Genomics. 2007 Oct;90(4):464-73. doi: 10.1016/j.ygeno.2007.06.004. Epub 2007 Aug 23. Genomics. 2007. PMID: 17719200 Free article.

8

T lymphocyte activation gene identification by coregulated expression on DNA microarrays.

Mao M, Biery MC, Kobayashi SV, Ward T, Schimmack G, Burchard J, Schelter JM, Dai H, He YD, Linsley PS. Mao M, et al. Genomics. 2004 Jun;83(6):989-99. doi: 10.1016/j.ygeno.2003.12.019. Genomics. 2004. PMID: 15177553

9

Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression.

Hartley DP, Dai X, He YD, Carlini EJ, Wang B, Huskey SE, Ulrich RG, Rushmore TH, Evers R, Evans DC. Hartley DP, et al. Mol Pharmacol. 2004 May;65(5):1159-71. doi: 10.1124/mol.65.5.1159. Mol Pharmacol. 2004. PMID: 15102944

10

Identification of potential pharmacological and toxicological targets differentiating structural analogs by a combination of transcriptional profiling and promoter analysis in LS-180 and Caco-2 adenocarcinoma cell lines.

Hartley DP, Dai X, Yabut J, Chu X, Cheng O, Zhang T, He YD, Roberts C, Ulrich R, Evers R, Evans DC. Hartley DP, et al. Pharmacogenet Genomics. 2006 Aug;16(8):579-99. doi: 10.1097/01.fpc.0000220561.59972.7a. Pharmacogenet Genomics. 2006. PMID: 16847427

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