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Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.
Pollard PJ, Brière JJ, Alam NA, Barwell J, Barclay E, Wortham NC, Hunt T, Mitchell M, Olpin S, Moat SJ, Hargreaves IP, Heales SJ, Chung YL, Griffiths JR, Dalgleish A, McGrath JA, Gleeson MJ, Hodgson SV, Poulsom R, Rustin P, Tomlinson IP. Pollard PJ, et al. Among authors: heales sj. Hum Mol Genet. 2005 Aug 1;14(15):2231-9. doi: 10.1093/hmg/ddi227. Epub 2005 Jun 29. Hum Mol Genet. 2005. PMID: 15987702
Statins and myopathy.
Hargreaves IP, Heales S. Hargreaves IP, et al. Lancet. 2002 Feb 23;359(9307):711-2. doi: 10.1016/S0140-6736(02)07795-4. Lancet. 2002. PMID: 11879898 No abstract available.
PINK1 protein in normal human brain and Parkinson's disease.
Gandhi S, Muqit MM, Stanyer L, Healy DG, Abou-Sleiman PM, Hargreaves I, Heales S, Ganguly M, Parsons L, Lees AJ, Latchman DS, Holton JL, Wood NW, Revesz T. Gandhi S, et al. Brain. 2006 Jul;129(Pt 7):1720-31. doi: 10.1093/brain/awl114. Epub 2006 May 15. Brain. 2006. PMID: 16702191
Nitric oxide, energy metabolism and neurological disease.
Heales SJ, Barker JE, Stewart VC, Brand MP, Hargreaves IP, Foppa P, Land JM, Clark JB, Bolaños JP. Heales SJ, et al. Biochem Soc Trans. 1997 Aug;25(3):939-43. doi: 10.1042/bst0250939. Biochem Soc Trans. 1997. PMID: 9388577 Review. No abstract available.
236 results