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Heart rate reactivity, recovery, and endurance of the incremental shuttle walk test in patients prone to heart failure.
Wei FF, Mariottoni B, An DW, Pellicori P, Yu YL, Verdonschot JAJ, Liu C, Ahmed FZ, Petutschnigg J, Rossignol P, Heymans S, Cuthbert J, Girerd N, Li Y, Clark AL, Nawrot TS, Ferreira JP, Zannad F, Cleland JGF, Staessen JA; HOMAGE investigators. Wei FF, et al. ESC Heart Fail. 2024 Dec;11(6):4116-4126. doi: 10.1002/ehf2.15000. Epub 2024 Aug 11. ESC Heart Fail. 2024. PMID: 39129059 Free PMC article. Clinical Trial.
We addressed this issue by analysing the open HOMAGE (Heart OMics in Aging) trial. METHODS: In HOMAGE, 527 patients prone to heart failure were randomized to usual treatment with or without spironolactone (25-50 mg/day). ...The current findings demonst …
We addressed this issue by analysing the open HOMAGE (Heart OMics in Aging) trial. METHODS: In HOMAGE, 527 patients pro …
Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial.
Yu YL, Siwy J, An DW, González A, Hansen T, Latosinska A, Pellicori P, Ravassa S, Mariottoni B, Verdonschot JA, Ahmed F, Petutschnigg J, Rossignol P, Heymans S, Cuthbert JJ, Girerd N, Clark AL, Verhamme P, Nawrot TS, Janssens S, Cleland JG, Zannad F, Diez J, Mischak H, Ferreira JP, Staessen JA; HOMAGE investigators. Yu YL, et al. Heart. 2024 Sep 16;110(19):1180-1187. doi: 10.1136/heartjnl-2023-323796. Heart. 2024. PMID: 38729636 Free PMC article. Clinical Trial.
OBJECTIVE: Heart failure (HF) is characterised by collagen deposition. Urinary proteomic profiling (UPP) followed by peptide sequencing identifies parental proteins, for over 70% derived from collagens. ...METHODS: In this substudy (n=290) to the Heart 'Omics …
OBJECTIVE: Heart failure (HF) is characterised by collagen deposition. Urinary proteomic profiling (UPP) followed by peptide sequenci …