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Dilated cardiomyopathy-mediated heart failure induces a unique skeletal muscle myopathy with inflammation.
Song T, Manoharan P, Millay DP, Koch SE, Rubinstein J, Heiny JA, Sadayappan S. Song T, et al. Skelet Muscle. 2019 Jan 24;9(1):4. doi: 10.1186/s13395-019-0189-y. Skelet Muscle. 2019. PMID: 30678732 Free PMC article.
BACKGROUND: Skeletal muscle myopathy and exercise intolerance are diagnostic hallmarks of heart failure (HF). However, the molecular adaptations of skeletal muscles during dilated cardiomyopathy (DCM)-mediated HF are not completely …
BACKGROUND: Skeletal muscle myopathy and exercise intolerance are diagnostic hallmarks of heart failur
Aerobic exercise training improves skeletal muscle function and Ca2+ handling-related protein expression in sympathetic hyperactivity-induced heart failure.
Bueno CR Jr, Ferreira JC, Pereira MG, Bacurau AV, Brum PC. Bueno CR Jr, et al. J Appl Physiol (1985). 2010 Sep;109(3):702-9. doi: 10.1152/japplphysiol.00281.2010. Epub 2010 Jul 1. J Appl Physiol (1985). 2010. PMID: 20595538 Free article.
The cellular mechanisms of positive effects associated with aerobic exercise training on overall intrinsic skeletal muscle changes in heart failure (HF) remain unclear. ...We provide evidence that Ca2+ handling-related protein expression is decr …
The cellular mechanisms of positive effects associated with aerobic exercise training on overall intrinsic skeletal muscle
Autonomic, functional, skeletal muscle, and cardiac abnormalities are associated with increased ergoreflex sensitivity in mitochondrial disease.
Giannoni A, Aimo A, Mancuso M, Piepoli MF, Orsucci D, Aquaro GD, Barison A, De Marchi D, Taddei C, Cameli M, Raglianti V, Siciliano G, Passino C, Emdin M. Giannoni A, et al. Eur J Heart Fail. 2017 Dec;19(12):1701-1709. doi: 10.1002/ejhf.782. Epub 2017 Feb 24. Eur J Heart Fail. 2017. PMID: 28233467 Free article.
AIMS: Mitochondrial disease (MD) is a genetic disorder affecting skeletal muscles, with possible myocardial disease. The ergoreflex, sensitive to skeletal muscle work, regulates ventilatory and autonomic responses to exercise. ...METHODS AND RESULTS: T …
AIMS: Mitochondrial disease (MD) is a genetic disorder affecting skeletal muscles, with possible myocardial disease. The ergoreflex, …
Abnormal haemodynamic response to exercise in heart failure with preserved ejection fraction.
Bhella PS, Prasad A, Heinicke K, Hastings JL, Arbab-Zadeh A, Adams-Huet B, Pacini EL, Shibata S, Palmer MD, Newcomer BR, Levine BD. Bhella PS, et al. Eur J Heart Fail. 2011 Dec;13(12):1296-304. doi: 10.1093/eurjhf/hfr133. Epub 2011 Oct 5. Eur J Heart Fail. 2011. PMID: 21979991 Free PMC article.
AIMS: Peak oxygen uptake (VO(2)) is diminished in patients with heart failure with preserved ejection fraction (HFpEF) suggesting impaired cardiac reserve. ...The abnormal haemodynamic response to exercise (decreased peak VO(2), increased ΔQ(c)/ΔVO(2) slope) …
AIMS: Peak oxygen uptake (VO(2)) is diminished in patients with heart failure with preserved ejection fraction (HFpEF) suggest …
Inspiratory muscle weakness in diastolic dysfunction.
Lavietes MH, Gerula CM, Fless KG, Cherniack NS, Arora RR. Lavietes MH, et al. Chest. 2004 Sep;126(3):838-44. doi: 10.1378/chest.126.3.838. Chest. 2004. PMID: 15364764
BACKGROUND: Respiratory muscle weakness has been described in patients with (systolic) congestive heart failure; however, whether or not patients with DD may present with the findings of congestive heart failure is not known. ...Subjects then pe …
BACKGROUND: Respiratory muscle weakness has been described in patients with (systolic) congestive heart failure; howeve …
Skeletal muscle dysfunction in patients with idiopathic pulmonary arterial hypertension.
Bauer R, Dehnert C, Schoene P, Filusch A, Bärtsch P, Borst MM, Katus HA, Meyer FJ. Bauer R, et al. Respir Med. 2007 Nov;101(11):2366-9. doi: 10.1016/j.rmed.2007.06.014. Epub 2007 Aug 6. Respir Med. 2007. PMID: 17689235 Free article.
However, it has not been investigated whether this respiratory muscle weakness might be part of a general muscle dysfunction as observed in congestive left heart failure. ...The correlation with respiratory muscle dysfunction and severity of dis …
However, it has not been investigated whether this respiratory muscle weakness might be part of a general muscle dysfunction a …
[The prognostic value of type-1 myosin heavy chain in the skeletal muscle of patients with chronic heart failure of a mild-moderate degree].
Serafini F, Franceschini M, Vescovo G, Ambrosio GB. Serafini F, et al. Cardiologia. 1998 Oct;43(10):1059-66. Cardiologia. 1998. PMID: 9922570 Italian.
Patients with chronic heart failure (CHF) develop skeletal muscle disease (myopathy) that is in part responsible for the decrease of their exercise tolerance. ...At baseline all subjects performed cardiopulmonary exercise
Patients with chronic heart failure (CHF) develop skeletal muscle disease (myopathy) that is in part resp …
[Cardiac manifestation of progressive muscular dystrophy of the Duchenne type].
Angermann C, Spes C, Pongratz D. Angermann C, et al. Z Kardiol. 1986 Sep;75(9):542-51. Z Kardiol. 1986. PMID: 3788261 German.
Thus, clinical symptoms during A suggested latent congestive heart failure in many of the patients, and echocardiography identified provokable contraction abnormalities of such segments of the ventricular wall known to be most frequently involved in the dystr …
Thus, clinical symptoms during A suggested latent congestive heart failure in many of the patients, and echocardiography
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