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[Pharmacological treatment options for prevention of alcohol relapse].
Heberlein A, Bleich S, Kornhuber J, Hillemacher T. Heberlein A, et al. Fortschr Neurol Psychiatr. 2008 Jul;76(7):421-8. doi: 10.1055/s-2008-1038220. Fortschr Neurol Psychiatr. 2008. PMID: 18604776 Review. German.
Decreased galanin serum levels are associated with alcohol-craving during withdrawal.
Heberlein A, Muschler M, Frieling H, Lenz B, Wilhelm J, Gröschl M, Kornhuber J, Bleich S, Hillemacher T. Heberlein A, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Mar 30;35(2):568-72. doi: 10.1016/j.pnpbp.2010.12.021. Epub 2010 Dec 31. Prog Neuropsychopharmacol Biol Psychiatry. 2011. PMID: 21199668
We found a significant negative association between the galanin serum levels and alcohol craving measured by the Obsessive Compulsive Drinking Scale (OCDS) (r=-0.449, p=0.009) and the obsessive subscale of the OCDS (r=-0.521, p=0.002) on day 1 of alcohol withdrawal. ...
We found a significant negative association between the galanin serum levels and alcohol craving measured by the Obsessive Compulsive …
BDNF and GDNF serum levels in alcohol-dependent patients during withdrawal.
Heberlein A, Muschler M, Wilhelm J, Frieling H, Lenz B, Gröschl M, Kornhuber J, Bleich S, Hillemacher T. Heberlein A, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Aug 16;34(6):1060-4. doi: 10.1016/j.pnpbp.2010.05.025. Epub 2010 May 27. Prog Neuropsychopharmacol Biol Psychiatry. 2010. PMID: 20553781
Do changes in the BDNF promoter methylation indicate the risk of alcohol relapse?
Heberlein A, Büscher P, Schuster R, Kleimann A, Lichtinghagen R, Rhein M, Kornhuber J, Bleich S, Frieling H, Hillemacher T. Heberlein A, et al. Eur Neuropsychopharmacol. 2015 Nov;25(11):1892-7. doi: 10.1016/j.euroneuro.2015.08.018. Epub 2015 Sep 5. Eur Neuropsychopharmacol. 2015. PMID: 26404404
In particular, we aimed to investigate a possible association between the BDNF promoter methylation and the self-reported duration of alcohol abstinence before relapse. ...
In particular, we aimed to investigate a possible association between the BDNF promoter methylation and the self-reported duration of …
TNF-α and IL-6 serum levels: neurobiological markers of alcohol consumption in alcohol-dependent patients?
Heberlein A, Käser M, Lichtinghagen R, Rhein M, Lenz B, Kornhuber J, Bleich S, Hillemacher T. Heberlein A, et al. Alcohol. 2014 Nov;48(7):671-6. doi: 10.1016/j.alcohol.2014.08.003. Epub 2014 Aug 15. Alcohol. 2014. PMID: 25262503
Moreover, we found a significant association between the BDNF serum levels and the TNF-α serum levels (r = -0.426, p = 0.021). ...
Moreover, we found a significant association between the BDNF serum levels and the TNF-α serum levels (r = -0.426, p = 0.021). ...
The treatment of alcohol and opioid dependence in pregnant women.
Heberlein A, Leggio L, Stichtenoth D, Hillemacher T. Heberlein A, et al. Curr Opin Psychiatry. 2012 Nov;25(6):559-64. doi: 10.1097/YCO.0b013e328358ad36. Curr Opin Psychiatry. 2012. PMID: 23037965 Free PMC article. Review.
Increased levels of adiponectin and resistin in alcohol dependence--possible link to craving.
Hillemacher T, Weinland C, Heberlein A, Gröschl M, Schanze A, Frieling H, Wilhelm J, Kornhuber J, Bleich S. Hillemacher T, et al. Drug Alcohol Depend. 2009 Jan 1;99(1-3):333-7. doi: 10.1016/j.drugalcdep.2008.07.019. Epub 2008 Sep 24. Drug Alcohol Depend. 2009. PMID: 18818026
Recent studies suggested a role of appetite regulating peptides like leptin and ghrelin in alcohol dependence and particularly in the neurobiology of alcohol craving. ...We analyzed a sample of 88 patients at admission for alcohol detoxification and after 1 week of …
Recent studies suggested a role of appetite regulating peptides like leptin and ghrelin in alcohol dependence and particularly in the …
Role of appetite-regulating peptides in alcohol craving: an analysis in respect to subtypes and different consumption patterns in alcoholism.
Hillemacher T, Kraus T, Rauh J, Weiss J, Schanze A, Frieling H, Wilhelm J, Heberlein A, Gröschl M, Sperling W, Kornhuber J, Bleich S. Hillemacher T, et al. Alcohol Clin Exp Res. 2007 Jun;31(6):950-4. doi: 10.1111/j.1530-0277.2007.00388.x. Epub 2007 Apr 13. Alcohol Clin Exp Res. 2007. PMID: 17433008
METHODS: We analyzed a sample of 188 patients at admission for alcohol detoxification regarding leptin and ghrelin (n=117) serum levels. ...RESULTS: Using general linear models to analyze a possible interaction between subtypes and leptin/ghrelin levels with respect …
METHODS: We analyzed a sample of 188 patients at admission for alcohol detoxification regarding leptin and ghrelin (n=117) serum leve …
NGF plasma levels increase due to alcohol intoxication and decrease during withdrawal.
Heberlein A, Bleich S, Bayerlein K, Frieling H, Gröschl M, Kornhuber J, Hillemacher T. Heberlein A, et al. Psychoneuroendocrinology. 2008 Aug;33(7):999-1003. doi: 10.1016/j.psyneuen.2008.05.011. Epub 2008 Jul 21. Psychoneuroendocrinology. 2008. PMID: 18639986
From day 0 to day 7 of alcohol withdrawal NGF plasma levels decreased significantly in both groups (group A: Z=-3.118, p=0.002, group B: Z=-2.103, p=0.035). ...These results suggest that NGF plasma levels increase as part of a regulation mechanism that counteracts a …
From day 0 to day 7 of alcohol withdrawal NGF plasma levels decreased significantly in both groups (group A: Z=-3.118, p=0.002, group …
The implications for the biological and sociodynamic causal explanations of attitudes toward alcohol-dependent patients.
Heberlein A, Schuster R, Ziert Y, Opfermann B, Bleich S, Hillemacher T. Heberlein A, et al. Psychiatry Res. 2014 Mar 30;215(3):766-70. doi: 10.1016/j.psychres.2013.12.040. Epub 2014 Jan 4. Psychiatry Res. 2014. PMID: 24439300
We investigated the effect of information leaflets on 444 participants: one group received an information leaflet with a biological explanation of AD; the other received a leaflet with a sole sociodynamic explanation of AD. A third, control group did n …
We investigated the effect of information leaflets on 444 participants: one group received an information leaflet with a biological e …
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