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Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.
Li XY, MacArthur S, Bourgon R, Nix D, Pollard DA, Iyer VN, Hechmer A, Simirenko L, Stapleton M, Luengo Hendriks CL, Chu HC, Ogawa N, Inwood W, Sementchenko V, Beaton A, Weiszmann R, Celniker SE, Knowles DW, Gingeras T, Speed TP, Eisen MB, Biggin MD. Li XY, et al. Among authors: hechmer a. PLoS Biol. 2008 Feb;6(2):e27. doi: 10.1371/journal.pbio.0060027. PLoS Biol. 2008. PMID: 18271625 Free PMC article.
Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions.
MacArthur S, Li XY, Li J, Brown JB, Chu HC, Zeng L, Grondona BP, Hechmer A, Simirenko L, Keränen SV, Knowles DW, Stapleton M, Bickel P, Biggin MD, Eisen MB. MacArthur S, et al. Among authors: hechmer a. Genome Biol. 2009;10(7):R80. doi: 10.1186/gb-2009-10-7-r80. Epub 2009 Jul 23. Genome Biol. 2009. PMID: 19627575 Free PMC article.
Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer.
Bouhaddou M, Lee RH, Li H, Bhola NE, O'Keefe RA, Naser M, Zhu TR, Nwachuku K, Duvvuri U, Olshen AB, Roy R, Hechmer A, Bolen J, Keysar SB, Jimeno A, Mills GB, Vandenberg S, Swaney DL, Johnson DE, Krogan NJ, Grandis JR. Bouhaddou M, et al. Among authors: hechmer a. JCI Insight. 2021 Oct 22;6(20):e151982. doi: 10.1172/jci.insight.151982. JCI Insight. 2021. PMID: 34546978 Free PMC article.
Association between Ancestry-Specific 6q25 Variants and Breast Cancer Subtypes in Peruvian Women.
Zavala VA, Casavilca-Zambrano S, Navarro-Vásquez J, Castañeda CA, Valencia G, Morante Z, Calderón M, Abugattas JE, Gómez H, Fuentes HA, Liendo-Picoaga R, Cotrina JM, Monge C, Neciosup SP, Huntsman S, Hu D, Sánchez SE, Williams MA, Núñez-Marrero A, Godoy L, Hechmer A, Olshen AB, Dutil J, Ziv E, Zabaleta J, Gelaye B, Vásquez J, Gálvez-Nino M, Enriquez-Vera D, Vidaurre T, Fejerman L. Zavala VA, et al. Among authors: hechmer a. Cancer Epidemiol Biomarkers Prev. 2022 Aug 2;31(8):1602-1609. doi: 10.1158/1055-9965.EPI-22-0069. Cancer Epidemiol Biomarkers Prev. 2022. PMID: 35654312 Free PMC article.
Molecular and phenotypic diversity of CBL-mutated juvenile myelomonocytic leukemia.
Hecht A, Meyer JA, Behnert A, Wong E, Chehab F, Olshen A, Hechmer A, Aftandilian C, Bhat R, Choi SW, Chonat S, Farrar JE, Fluchel M, Frangoul H, Han JH, Kolb EA, Kuo DJ, MacMillan ML, Maese L, Maloney KW, Narendran A, Oshrine B, Schultz KR, Sulis ML, Van Mater D, Tasian SK, Hofmann WK, Loh ML, Stieglitz E. Hecht A, et al. Among authors: hechmer a. Haematologica. 2022 Jan 1;107(1):178-186. doi: 10.3324/haematol.2020.270595. Haematologica. 2022. PMID: 33375775 Free PMC article.