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Small-molecule inhibition of APT1 affects Ras localization and signaling.
Dekker FJ, Rocks O, Vartak N, Menninger S, Hedberg C, Balamurugan R, Wetzel S, Renner S, Gerauer M, Schölermann B, Rusch M, Kramer JW, Rauh D, Coates GW, Brunsveld L, Bastiaens PI, Waldmann H. Dekker FJ, et al. Among authors: hedberg c. Nat Chem Biol. 2010 Jun;6(6):449-56. doi: 10.1038/nchembio.362. Epub 2010 Apr 25. Nat Chem Biol. 2010. PMID: 20418879
Chemical biology of lipidated proteins.
Triola G, Waldmann H, Hedberg C. Triola G, et al. Among authors: hedberg c. ACS Chem Biol. 2012 Jan 20;7(1):87-99. doi: 10.1021/cb200460u. Epub 2012 Jan 4. ACS Chem Biol. 2012. PMID: 22148864 Review.
Boron-based inhibitors of acyl protein thioesterases 1 and 2.
Zimmermann TJ, Bürger M, Tashiro E, Kondoh Y, Martinez NE, Görmer K, Rosin-Steiner S, Shimizu T, Ozaki S, Mikoshiba K, Watanabe N, Hall D, Vetter IR, Osada H, Hedberg C, Waldmann H. Zimmermann TJ, et al. Among authors: hedberg c. Chembiochem. 2013 Jan 2;14(1):115-22. doi: 10.1002/cbic.201200571. Epub 2012 Dec 13. Chembiochem. 2013. PMID: 23239555
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis.
Siegel G, Obernosterer G, Fiore R, Oehmen M, Bicker S, Christensen M, Khudayberdiev S, Leuschner PF, Busch CJ, Kane C, Hübel K, Dekker F, Hedberg C, Rengarajan B, Drepper C, Waldmann H, Kauppinen S, Greenberg ME, Draguhn A, Rehmsmeier M, Martinez J, Schratt GM. Siegel G, et al. Among authors: hedberg c. Nat Cell Biol. 2009 Jun;11(6):705-16. doi: 10.1038/ncb1876. Epub 2009 May 24. Nat Cell Biol. 2009. PMID: 19465924 Free PMC article.
Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway.
Simon S, Schell U, Heuer N, Hager D, Albers MF, Matthias J, Fahrnbauer F, Trauner D, Eichinger L, Hedberg C, Hilbi H. Simon S, et al. Among authors: hedberg c. PLoS Pathog. 2015 Dec 3;11(12):e1005307. doi: 10.1371/journal.ppat.1005307. eCollection 2015 Dec. PLoS Pathog. 2015. PMID: 26633832 Free PMC article.
271 results