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Hypoxia inducible factors in cancer stem cells.
Heddleston JM, Li Z, Lathia JD, Bao S, Hjelmeland AB, Rich JN. Heddleston JM, et al. Br J Cancer. 2010 Mar 2;102(5):789-95. doi: 10.1038/sj.bjc.6605551. Epub 2010 Jan 26. Br J Cancer. 2010. PMID: 20104230 Free PMC article. Review.
Targeting A20 decreases glioma stem cell survival and tumor growth.
Hjelmeland AB, Wu Q, Wickman S, Eyler C, Heddleston J, Shi Q, Lathia JD, Macswords J, Lee J, McLendon RE, Rich JN. Hjelmeland AB, et al. PLoS Biol. 2010 Feb 23;8(2):e1000319. doi: 10.1371/journal.pbio.1000319. PLoS Biol. 2010. PMID: 20186265 Free PMC article.
Acidic stress promotes a glioma stem cell phenotype.
Hjelmeland AB, Wu Q, Heddleston JM, Choudhary GS, MacSwords J, Lathia JD, McLendon R, Lindner D, Sloan A, Rich JN. Hjelmeland AB, et al. Among authors: heddleston jm. Cell Death Differ. 2011 May;18(5):829-40. doi: 10.1038/cdd.2010.150. Epub 2010 Dec 3. Cell Death Differ. 2011. PMID: 21127501 Free PMC article.
Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions.
Lathia JD, Hitomi M, Gallagher J, Gadani SP, Adkins J, Vasanji A, Liu L, Eyler CE, Heddleston JM, Wu Q, Minhas S, Soeda A, Hoeppner DJ, Ravin R, McKay RD, McLendon RE, Corbeil D, Chenn A, Hjelmeland AB, Park DM, Rich JN. Lathia JD, et al. Among authors: heddleston jm. Cell Death Dis. 2011 Sep 1;2(9):e200. doi: 10.1038/cddis.2011.80. Cell Death Dis. 2011. PMID: 21881602 Free PMC article.
Integrin alpha 6 regulates glioblastoma stem cells.
Lathia JD, Gallagher J, Heddleston JM, Wang J, Eyler CE, Macswords J, Wu Q, Vasanji A, McLendon RE, Hjelmeland AB, Rich JN. Lathia JD, et al. Among authors: heddleston jm. Cell Stem Cell. 2010 May 7;6(5):421-32. doi: 10.1016/j.stem.2010.02.018. Cell Stem Cell. 2010. PMID: 20452317 Free PMC article.
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3.
Guryanova OA, Wu Q, Cheng L, Lathia JD, Huang Z, Yang J, MacSwords J, Eyler CE, McLendon RE, Heddleston JM, Shou W, Hambardzumyan D, Lee J, Hjelmeland AB, Sloan AE, Bredel M, Stark GR, Rich JN, Bao S. Guryanova OA, et al. Among authors: heddleston jm. Cancer Cell. 2011 Apr 12;19(4):498-511. doi: 10.1016/j.ccr.2011.03.004. Cancer Cell. 2011. PMID: 21481791 Free PMC article.
HIF induces human embryonic stem cell markers in cancer cells.
Mathieu J, Zhang Z, Zhou W, Wang AJ, Heddleston JM, Pinna CM, Hubaud A, Stadler B, Choi M, Bar M, Tewari M, Liu A, Vessella R, Rostomily R, Born D, Horwitz M, Ware C, Blau CA, Cleary MA, Rich JN, Ruohola-Baker H. Mathieu J, et al. Among authors: heddleston jm. Cancer Res. 2011 Jul 1;71(13):4640-52. doi: 10.1158/0008-5472.CAN-10-3320. Epub 2011 Jun 28. Cancer Res. 2011. PMID: 21712410 Free PMC article.
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