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31 results
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Cloning of a Xenopus laevis inwardly rectifying K+ channel subunit that permits GIRK1 expression of IKACh currents in oocytes.
Hedin KE, Lim NF, Clapham DE. Hedin KE, et al. Neuron. 1996 Feb;16(2):423-9. doi: 10.1016/s0896-6273(00)80060-4. Neuron. 1996. PMID: 8789957
Specificity of receptor-G protein interactions: searching for the structure behind the signal.
Hedin KE, Duerson K, Clapham DE. Hedin KE, et al. Cell Signal. 1993 Sep;5(5):505-18. doi: 10.1016/0898-6568(93)90046-o. Cell Signal. 1993. PMID: 8312128 Review. No abstract available.
TCR-CXCR4 signaling stabilizes cytokine mRNA transcripts via a PREX1-Rac1 pathway: implications for CTCL.
Kremer KN, Dinkel BA, Sterner RM, Osborne DG, Jevremovic D, Hedin KE. Kremer KN, et al. Among authors: hedin ke. Blood. 2017 Aug 24;130(8):982-994. doi: 10.1182/blood-2017-03-770982. Epub 2017 Jul 10. Blood. 2017. PMID: 28694325 Free PMC article.
G alpha i2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions.
Kremer KN, Kumar A, Hedin KE. Kremer KN, et al. Among authors: hedin ke. J Immunol. 2011 Sep 15;187(6):3177-85. doi: 10.4049/jimmunol.1100206. Epub 2011 Aug 19. J Immunol. 2011. PMID: 21856938 Free PMC article.
Chemokines: new, key players in the pathobiology of pancreatic cancer.
Hedin KE. Hedin KE. Int J Gastrointest Cancer. 2002;31(1-3):23-9. doi: 10.1385/IJGC:31:1-3:23. Int J Gastrointest Cancer. 2002. PMID: 12622412 Review.
Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine.
Kremer KN, Humphreys TD, Kumar A, Qian NX, Hedin KE. Kremer KN, et al. Among authors: hedin ke. J Immunol. 2003 Jul 1;171(1):360-7. doi: 10.4049/jimmunol.171.1.360. J Immunol. 2003. PMID: 12817019
CXCR4 physically associates with the T cell receptor to signal in T cells.
Kumar A, Humphreys TD, Kremer KN, Bramati PS, Bradfield L, Edgar CE, Hedin KE. Kumar A, et al. Among authors: hedin ke. Immunity. 2006 Aug;25(2):213-24. doi: 10.1016/j.immuni.2006.06.015. Immunity. 2006. PMID: 16919488
Gi proteins use a novel beta gamma- and Ras-independent pathway to activate extracellular signal-regulated kinase and mobilize AP-1 transcription factors in Jurkat T lymphocytes.
Hedin KE, Bell MP, Huntoon CJ, Karnitz LM, McKean DJ. Hedin KE, et al. J Biol Chem. 1999 Jul 9;274(28):19992-20001. doi: 10.1074/jbc.274.28.19992. J Biol Chem. 1999. PMID: 10391949
β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma.
Clift IC, Bamidele AO, Rodriguez-Ramirez C, Kremer KN, Hedin KE. Clift IC, et al. Among authors: hedin ke. Mol Pharmacol. 2014 Apr;85(4):542-52. doi: 10.1124/mol.113.089714. Epub 2014 Jan 22. Mol Pharmacol. 2014. PMID: 24452472 Free PMC article.
Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses.
Kremer KN, Clift IC, Miamen AG, Bamidele AO, Qian NX, Humphreys TD, Hedin KE. Kremer KN, et al. Among authors: hedin ke. J Immunol. 2011 Aug 1;187(3):1440-7. doi: 10.4049/jimmunol.1100820. Epub 2011 Jun 24. J Immunol. 2011. PMID: 21705626 Free PMC article.
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