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Condensin, chromatin crossbarring and chromosome condensation.
Thadani R, Uhlmann F, Heeger S. Thadani R, et al. Among authors: heeger s. Curr Biol. 2012 Dec 4;22(23):R1012-21. doi: 10.1016/j.cub.2012.10.023. Curr Biol. 2012. PMID: 23218009 Free article. Review.
Cell-Cycle Regulation of Dynamic Chromosome Association of the Condensin Complex.
Thadani R, Kamenz J, Heeger S, Muñoz S, Uhlmann F. Thadani R, et al. Among authors: heeger s. Cell Rep. 2018 May 22;23(8):2308-2317. doi: 10.1016/j.celrep.2018.04.082. Cell Rep. 2018. PMID: 29791843 Free PMC article.
A simple biophysical model emulates budding yeast chromosome condensation.
Cheng TM, Heeger S, Chaleil RA, Matthews N, Stewart A, Wright J, Lim C, Bates PA, Uhlmann F. Cheng TM, et al. Among authors: heeger s. Elife. 2015 Apr 29;4:e05565. doi: 10.7554/eLife.05565. Elife. 2015. PMID: 25922992 Free PMC article.
Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion.
Rolef Ben-Shahar T, Heeger S, Lehane C, East P, Flynn H, Skehel M, Uhlmann F. Rolef Ben-Shahar T, et al. Among authors: heeger s. Science. 2008 Jul 25;321(5888):563-6. doi: 10.1126/science.1157774. Science. 2008. PMID: 18653893
Replicated chromosomes are held together by the chromosomal cohesin complex from the time of their synthesis in S phase onward. This requires the replication fork-associated acetyl transferase Eco1, but Eco1's mechanism of action is not known. We identified spontane …
Replicated chromosomes are held together by the chromosomal cohesin complex from the time of their synthesis in S phase onward. This …
The mitotic arrest in response to hypoxia and of polar bodies during early embryogenesis requires Drosophila Mps1.
Fischer MG, Heeger S, Häcker U, Lehner CF. Fischer MG, et al. Among authors: heeger s. Curr Biol. 2004 Nov 23;14(22):2019-24. doi: 10.1016/j.cub.2004.11.008. Curr Biol. 2004. PMID: 15556864
Rapid effects of acute anoxia on spindle kinetochore interactions activate the mitotic spindle checkpoint.
Pandey R, Heeger S, Lehner CF. Pandey R, et al. Among authors: heeger s. J Cell Sci. 2007 Aug 15;120(Pt 16):2807-18. doi: 10.1242/jcs.007690. Epub 2007 Jul 24. J Cell Sci. 2007. PMID: 17652159
Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes.
Schittenhelm RB, Heeger S, Althoff F, Walter A, Heidmann S, Mechtler K, Lehner CF. Schittenhelm RB, et al. Among authors: heeger s. Chromosoma. 2007 Aug;116(4):385-402. doi: 10.1007/s00412-007-0103-y. Epub 2007 Mar 1. Chromosoma. 2007. PMID: 17333235 Free PMC article.
Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog.
Heeger S, Leismann O, Schittenhelm R, Schraidt O, Heidmann S, Lehner CF. Heeger S, et al. Genes Dev. 2005 Sep 1;19(17):2041-53. doi: 10.1101/gad.347805. Genes Dev. 2005. PMID: 16140985 Free PMC article.
Evaluation of EGFR inhibitor-mediated acneiform skin toxicity within the double-blind randomized EVITA trial: A thorough gender-specific analysis using the WoMo score.
Gaiser MR, Lorenzen S, Merx K, Trojan J, Ocvirk J, Ettrich TJ, Al-Batran SE, Schulz H, Homann N, Feustel HP, Schatz M, Kripp M, Schulte N, Heeger S, Vlassak S, Koch W, Hofheinz RD. Gaiser MR, et al. Among authors: heeger s. Cancer Med. 2019 Aug;8(9):4169-4175. doi: 10.1002/cam4.2132. Epub 2019 Jun 14. Cancer Med. 2019. PMID: 31199595 Free PMC article. Clinical Trial.
Vitamin K1 cream significantly reduces incidence and severity of cetuximab-related acneiform skin rash in women: a post hoc analysis of the EVITA trial.
Gaiser MR, Lorenzen S, Merx K, Trojan J, Ocvirk J, Ettrich TJ, Al-Batran SE, Schulz H, Homann N, Feustel HP, Schatz M, Kripp M, Schulte N, Heeger S, Vlassak S, Koch W, Hofheinz RD. Gaiser MR, et al. Among authors: heeger s. Ann Oncol. 2018 Dec 1;29(12):2393-2395. doi: 10.1093/annonc/mdy451. Ann Oncol. 2018. PMID: 30307464 Free article. Clinical Trial. No abstract available.
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