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Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers.
Li X, Zhou S, Abrahams CL, Krimm S, Smith J, Bajjuri K, Stephenson HT, Henningsen R, Hanson J, Heibeck TH, Calarese D, Tran C, Yin G, Stafford RL, Yam AY, Kline T, De Almeida VI, Sato AK, Lupher M, Bedard K, Hallam TJ. Li X, et al. Among authors: heibeck th. Mol Cancer Ther. 2023 Feb 1;22(2):155-167. doi: 10.1158/1535-7163.MCT-22-0322. Mol Cancer Ther. 2023. PMID: 36459691 Free PMC article.
RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates.
Yin G, Stephenson HT, Yang J, Li X, Armstrong SM, Heibeck TH, Tran C, Masikat MR, Zhou S, Stafford RL, Yam AY, Lee J, Steiner AR, Gill A, Penta K, Pollitt S, Baliga R, Murray CJ, Thanos CD, McEvoy LM, Sato AK, Hallam TJ. Yin G, et al. Among authors: heibeck th. Sci Rep. 2017 Jun 8;7(1):3026. doi: 10.1038/s41598-017-03192-z. Sci Rep. 2017. PMID: 28596531 Free PMC article.
Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system.
Zimmerman ES, Heibeck TH, Gill A, Li X, Murray CJ, Madlansacay MR, Tran C, Uter NT, Yin G, Rivers PJ, Yam AY, Wang WD, Steiner AR, Bajad SU, Penta K, Yang W, Hallam TJ, Thanos CD, Sato AK. Zimmerman ES, et al. Among authors: heibeck th. Bioconjug Chem. 2014 Feb 19;25(2):351-61. doi: 10.1021/bc400490z. Epub 2014 Jan 29. Bioconjug Chem. 2014. PMID: 24437342
Site-specific proteomics approach for study protein S-nitrosylation.
Liu M, Hou J, Huang L, Huang X, Heibeck TH, Zhao R, Pasa-Tolic L, Smith RD, Li Y, Fu K, Zhang Z, Hinrichs SH, Ding SJ. Liu M, et al. Among authors: heibeck th. Anal Chem. 2010 Sep 1;82(17):7160-8. doi: 10.1021/ac100569d. Anal Chem. 2010. PMID: 20687582
Endogenous 3,4-dihydroxyphenylalanine and dopaquinone modifications on protein tyrosine: links to mitochondrially derived oxidative stress via hydroxyl radical.
Zhang X, Monroe ME, Chen B, Chin MH, Heibeck TH, Schepmoes AA, Yang F, Petritis BO, Camp DG 2nd, Pounds JG, Jacobs JM, Smith DJ, Bigelow DJ, Smith RD, Qian WJ. Zhang X, et al. Among authors: heibeck th. Mol Cell Proteomics. 2010 Jun;9(6):1199-208. doi: 10.1074/mcp.M900321-MCP200. Epub 2010 Feb 2. Mol Cell Proteomics. 2010. PMID: 20124354 Free PMC article.
Quantitative phosphoproteome analysis of lysophosphatidic acid induced chemotaxis applying dual-step (18)O labeling coupled with immobilized metal-ion affinity chromatography.
Ding SJ, Wang Y, Jacobs JM, Qian WJ, Yang F, Tolmachev AV, Du X, Wang W, Moore RJ, Monroe ME, Purvine SO, Waters K, Heibeck TH, Adkins JN, Camp DG 2nd, Klemke RL, Smith RD. Ding SJ, et al. Among authors: heibeck th. J Proteome Res. 2008 Oct;7(10):4215-24. doi: 10.1021/pr7007785. Epub 2008 Sep 12. J Proteome Res. 2008. PMID: 18785766 Free PMC article.
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