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A multicenter, randomized, placebo controlled, multiple-dose, safety and pharmacokinetic study of AIT-082 (Neotrofin) in mild Alzheimer's disease patients.
Grundman M, Capparelli E, Kim HT, Morris JC, Farlow M, Rubin EH, Heidebrink J, Hake A, Ho G, Schultz AN, Schafer K, Houston W, Thomas R, Thal LJ; Alzheimer's Disease Cooperative Study. Grundman M, et al. Among authors: heidebrink j. Life Sci. 2003 Jun 20;73(5):539-53. doi: 10.1016/s0024-3205(03)00320-5. Life Sci. 2003. PMID: 12770610 Clinical Trial.
Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease.
Jack CR Jr, Lowe VJ, Weigand SD, Wiste HJ, Senjem ML, Knopman DS, Shiung MM, Gunter JL, Boeve BF, Kemp BJ, Weiner M, Petersen RC; Alzheimer's Disease Neuroimaging Initiative. Jack CR Jr, et al. Brain. 2009 May;132(Pt 5):1355-65. doi: 10.1093/brain/awp062. Epub 2009 Mar 31. Brain. 2009. PMID: 19339253 Free PMC article.
Subregional neuroanatomical change as a biomarker for Alzheimer's disease.
Holland D, Brewer JB, Hagler DJ, Fennema-Notestine C, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Holland D, et al. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20954-9. doi: 10.1073/pnas.0906053106. Proc Natl Acad Sci U S A. 2009. PMID: 19996185 Free PMC article.
Voxelwise genome-wide association study (vGWAS).
Stein JL, Hua X, Lee S, Ho AJ, Leow AD, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Dechairo BM, Potkin SG, Weiner MW, Thompson P; Alzheimer's Disease Neuroimaging Initiative. Stein JL, et al. Neuroimage. 2010 Nov 15;53(3):1160-74. doi: 10.1016/j.neuroimage.2010.02.032. Epub 2010 Feb 17. Neuroimage. 2010. PMID: 20171287 Free PMC article.
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly.
Ho AJ, Stein JL, Hua X, Lee S, Hibar DP, Leow AD, Dinov ID, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Stephan DA, DeCarli CS, DeChairo BM, Potkin SG, Jack CR Jr, Weiner MW, Raji CA, Lopez OL, Becker JT, Carmichael OT, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Ho AJ, et al. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8404-9. doi: 10.1073/pnas.0910878107. Epub 2010 Apr 19. Proc Natl Acad Sci U S A. 2010. PMID: 20404173 Free PMC article.
275 results