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Establishing a GMP-compliant manufacturing process and phase-appropriate analytics for early development of a FiCAR T-cell product with a novel CAR spacer.
Luostarinen A, Vuorela A, Kerkelä E, Patrikoski M, Kotovuori A, Koski J, Ahoniemi J, Lähteenmäki K, Lehtisalo J, Oja T, Paavilainen H, Autio A, Nyman M, Nikoskelainen V, Kergourlay V, Elbasani E, van Veen B, Thotakura A, Monzo H, Ojala PM, Korhonen M, Hongisto H, Laitinen A. Luostarinen A, et al. Among authors: hongisto h. Sci Rep. 2025 Mar 8;15(1):8093. doi: 10.1038/s41598-025-92736-9. Sci Rep. 2025. PMID: 40057567 Free PMC article.
Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients.
Karema-Jokinen V, Koskela A, Hytti M, Hongisto H, Viheriälä T, Liukkonen M, Torsti T, Skottman H, Kauppinen A, Nymark S, Kaarniranta K. Karema-Jokinen V, et al. Among authors: hongisto h. J Biol Chem. 2023 Jun;299(6):104770. doi: 10.1016/j.jbc.2023.104770. Epub 2023 May 1. J Biol Chem. 2023. PMID: 37137441 Free PMC article.
Novel Human Induced Pluripotent Stem Cell-Based Model for Retinal Pigment Epithelial Cells to Reveal Possible Disease Mechanisms for Macular Degeneration in Pseudoxanthoma Elasticum.
Viheriälä T, Hongisto H, Saari L, Oksanen M, Ilmarinen T, Väärämäki S, Uusitalo H, Nevalainen P, Skottman H. Viheriälä T, et al. Among authors: hongisto h. J Ophthalmol. 2024 Sep 21;2024:6939920. doi: 10.1155/2024/6939920. eCollection 2024. J Ophthalmol. 2024. PMID: 39347541 Free PMC article.
19 results