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Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2.
Harbison-Price N, Ferguson SA, Heikal A, Taiaroa G, Hards K, Nakatani Y, Rennison D, Brimble MA, El-Deeb IM, Bohlmann L, McDevitt CA, von Itzstein M, Walker MJ, Cook GM. Harbison-Price N, et al. Among authors: heikal a. mSphere. 2020 Mar 18;5(2):e00157-20. doi: 10.1128/mSphere.00157-20. mSphere. 2020. PMID: 32188750 Free PMC article.
Substituted sulfonamide bioisosteres of 8-hydroxyquinoline as zinc-dependent antibacterial compounds.
McGowan JE, Harper AD, Davison EK, Jeong JY, Mros S, Harbison-Price N, Van Zuylen EM, Knottenbelt MK, Heikal A, Ferguson SA, McConnell MA, Cook GM, Krittaphol W, Walker GF, Brimble MA, Rennison D. McGowan JE, et al. Among authors: heikal a. Bioorg Med Chem Lett. 2020 Jun 1;30(11):127110. doi: 10.1016/j.bmcl.2020.127110. Epub 2020 Mar 16. Bioorg Med Chem Lett. 2020. PMID: 32229060
Bridging the gap between a TB drug and its target.
Cook GM, Heikal A. Cook GM, et al. Among authors: heikal a. Sci Transl Med. 2012 Sep 5;4(150):150fs33. doi: 10.1126/scitranslmed.3004816. Sci Transl Med. 2012. PMID: 22956196
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