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Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis.
Hein DW. Hein DW. Mutat Res. 2002 Sep 30;506-507:65-77. doi: 10.1016/s0027-5107(02)00153-7. Mutat Res. 2002. PMID: 12351146 Review.
Acetyltransferases and susceptibility to chemicals.
Hein DW, Rustan TD, Doll MA, Bucher KD, Ferguson RJ, Feng Y, Furman EJ, Gray K. Hein DW, et al. Toxicol Lett. 1992 Dec;64-65 Spec No:123-30. doi: 10.1016/0378-4274(92)90181-i. Toxicol Lett. 1992. PMID: 1471166 Review.
Acetylator genotype-dependent N-acetylation of arylamines in vivo and in vitro by hepatic and extrahepatic organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus.
Hein DW, Rustan TD, Martin WJ, Bucher KD, Miller LS, Furman EJ. Hein DW, et al. Arch Toxicol. 1992;66(2):112-7. doi: 10.1007/BF02342504. Arch Toxicol. 1992. PMID: 1605725
Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver.
Hein DW, Rustan TD, Bucher KD, Martin WJ, Furman EJ. Hein DW, et al. Drug Metab Dispos. 1991 Sep-Oct;19(5):933-7. Drug Metab Dispos. 1991. PMID: 1686239
Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus.
Hein DW, Rustan TD, Bucher KD, Miller LS. Hein DW, et al. J Pharmacol Exp Ther. 1991 Nov;259(2):699-704. J Pharmacol Exp Ther. 1991. PMID: 1941618
Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
Ogolla F, Ferguson RJ, Kirlin WG, Trinidad A, Andrews AF, Mpezo M, Hein DW. Ogolla F, et al. Among authors: hein dw. Drug Metab Dispos. 1990 Sep-Oct;18(5):680-5. Drug Metab Dispos. 1990. PMID: 1981720
Acetylator genotype-dependent expression of arylamine N-acetyltransferase in human colon cytosol from non-cancer and colorectal cancer patients.
Kirlin WG, Ogolla F, Andrews AF, Trinidad A, Ferguson RJ, Yerokun T, Mpezo M, Hein DW. Kirlin WG, et al. Among authors: hein dw. Cancer Res. 1991 Jan 15;51(2):549-55. Cancer Res. 1991. PMID: 1985773
Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model.
Hein DW, Rustan TD, Bucher KD, Furman EJ, Martin WJ. Hein DW, et al. J Pharmacol Exp Ther. 1991 Jul 1;258(1):232-6. J Pharmacol Exp Ther. 1991. PMID: 2072298
Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase.
Trinidad A, Hein DW, Rustan TD, Ferguson RJ, Miller LS, Bucher KD, Kirlin WG, Ogolla F, Andrews AF. Trinidad A, et al. Among authors: hein dw. Cancer Res. 1990 Dec 15;50(24):7942-9. Cancer Res. 1990. PMID: 2253236
Relationship of Syrian inbred hamster acetylator genotype to the mutagenic activation of 2-aminofluorene.
Yerokun T, Hein DW, Ferguson RJ, Ogolla F, Heflich RH, Minor TY, Trinidad A, Kirlin WG, Andrews AF. Yerokun T, et al. Among authors: hein dw. Mutagenesis. 1990 May;5(3):233-9. doi: 10.1093/mutage/5.3.233. Mutagenesis. 1990. PMID: 2385177
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