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Regulation of cardiac hypertrophy by intracellular signalling pathways.
Heineke J, Molkentin JD. Heineke J, et al. Nat Rev Mol Cell Biol. 2006 Aug;7(8):589-600. doi: 10.1038/nrm1983. Nat Rev Mol Cell Biol. 2006. PMID: 16936699 Review.
Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart.
Heineke J, Auger-Messier M, Xu J, Oka T, Sargent MA, York A, Klevitsky R, Vaikunth S, Duncan SA, Aronow BJ, Robbins J, Crombleholme TM, Molkentin JD. Heineke J, et al. J Clin Invest. 2007 Nov;117(11):3198-210. doi: 10.1172/JCI32573. J Clin Invest. 2007. PMID: 17975667 Free PMC article.
Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure.
Heineke J, Auger-Messier M, Xu J, Sargent M, York A, Welle S, Molkentin JD. Heineke J, et al. Circulation. 2010 Jan 26;121(3):419-25. doi: 10.1161/CIRCULATIONAHA.109.882068. Epub 2010 Jan 11. Circulation. 2010. PMID: 20065166 Free PMC article.
CIB1 is a regulator of pathological cardiac hypertrophy.
Heineke J, Auger-Messier M, Correll RN, Xu J, Benard MJ, Yuan W, Drexler H, Parise LV, Molkentin JD. Heineke J, et al. Nat Med. 2010 Aug;16(8):872-9. doi: 10.1038/nm.2181. Epub 2010 Jul 18. Nat Med. 2010. PMID: 20639889 Free PMC article.
Screening for novel calcium-binding proteins that regulate cardiac hypertrophy: CIB1 as an example.
Heineke J. Heineke J. Methods Mol Biol. 2013;963:279-301. doi: 10.1007/978-1-62703-230-8_17. Methods Mol Biol. 2013. PMID: 23296617
Calcineurin protects the heart in a murine model of dilated cardiomyopathy.
Heineke J, Wollert KC, Osinska H, Sargent MA, York AJ, Robbins J, Molkentin JD. Heineke J, et al. J Mol Cell Cardiol. 2010 Jun;48(6):1080-7. doi: 10.1016/j.yjmcc.2009.10.012. Epub 2009 Oct 22. J Mol Cell Cardiol. 2010. PMID: 19854199 Free PMC article.
Antiandrogenic therapy with finasteride attenuates cardiac hypertrophy and left ventricular dysfunction.
Zwadlo C, Schmidtmann E, Szaroszyk M, Kattih B, Froese N, Hinz H, Schmitto JD, Widder J, Batkai S, Bähre H, Kaever V, Thum T, Bauersachs J, Heineke J. Zwadlo C, et al. Among authors: heineke j. Circulation. 2015 Mar 24;131(12):1071-81. doi: 10.1161/CIRCULATIONAHA.114.012066. Epub 2015 Jan 28. Circulation. 2015. PMID: 25632043
Myostatin from the heart: local and systemic actions in cardiac failure and muscle wasting.
Breitbart A, Auger-Messier M, Molkentin JD, Heineke J. Breitbart A, et al. Among authors: heineke j. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H1973-82. doi: 10.1152/ajpheart.00200.2011. Epub 2011 Mar 18. Am J Physiol Heart Circ Physiol. 2011. PMID: 21421824 Free PMC article. Review.
MicroRNA-24 regulates vascularity after myocardial infarction.
Fiedler J, Jazbutyte V, Kirchmaier BC, Gupta SK, Lorenzen J, Hartmann D, Galuppo P, Kneitz S, Pena JT, Sohn-Lee C, Loyer X, Soutschek J, Brand T, Tuschl T, Heineke J, Martin U, Schulte-Merker S, Ertl G, Engelhardt S, Bauersachs J, Thum T. Fiedler J, et al. Among authors: heineke j. Circulation. 2011 Aug 9;124(6):720-30. doi: 10.1161/CIRCULATIONAHA.111.039008. Epub 2011 Jul 25. Circulation. 2011. PMID: 21788589
Cardiomyocyte calcineurin signaling in subcellular domains: from the sarcolemma to the nucleus and beyond.
Heineke J, Ritter O. Heineke J, et al. J Mol Cell Cardiol. 2012 Jan;52(1):62-73. doi: 10.1016/j.yjmcc.2011.10.018. Epub 2011 Oct 29. J Mol Cell Cardiol. 2012. PMID: 22064325 Review.
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