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Stabilization of beta-catenin induces pancreas tumor formation.
Heiser PW, Cano DA, Landsman L, Kim GE, Kench JG, Klimstra DS, Taketo MM, Biankin AV, Hebrok M. Heiser PW, et al. Gastroenterology. 2008 Oct;135(4):1288-300. doi: 10.1053/j.gastro.2008.06.089. Epub 2008 Jul 9. Gastroenterology. 2008. PMID: 18725219 Free PMC article.
Stabilization of beta-catenin impacts pancreas growth.
Heiser PW, Lau J, Taketo MM, Herrera PL, Hebrok M. Heiser PW, et al. Development. 2006 May;133(10):2023-32. doi: 10.1242/dev.02366. Epub 2006 Apr 12. Development. 2006. PMID: 16611688
Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.
Pasca di Magliano M, Biankin AV, Heiser PW, Cano DA, Gutierrez PJ, Deramaudt T, Segara D, Dawson AC, Kench JG, Henshall SM, Sutherland RL, Dlugosz A, Rustgi AK, Hebrok M. Pasca di Magliano M, et al. Among authors: heiser pw. PLoS One. 2007 Nov 7;2(11):e1155. doi: 10.1371/journal.pone.0001155. PLoS One. 2007. PMID: 17982507 Free PMC article.
Regulated beta-cell regeneration in the adult mouse pancreas.
Cano DA, Rulifson IC, Heiser PW, Swigart LB, Pelengaris S, German M, Evan GI, Bluestone JA, Hebrok M. Cano DA, et al. Among authors: heiser pw. Diabetes. 2008 Apr;57(4):958-66. doi: 10.2337/db07-0913. Epub 2007 Dec 14. Diabetes. 2008. PMID: 18083786
Wnt signaling regulates pancreatic beta cell proliferation.
Rulifson IC, Karnik SK, Heiser PW, ten Berge D, Chen H, Gu X, Taketo MM, Nusse R, Hebrok M, Kim SK. Rulifson IC, et al. Among authors: heiser pw. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6247-52. doi: 10.1073/pnas.0701509104. Epub 2007 Apr 2. Proc Natl Acad Sci U S A. 2007. PMID: 17404238 Free PMC article.
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M. Thayer SP, et al. Among authors: heiser pw. Nature. 2003 Oct 23;425(6960):851-6. doi: 10.1038/nature02009. Epub 2003 Sep 14. Nature. 2003. PMID: 14520413 Free PMC article.
A screen for regulators of survival of motor neuron protein levels.
Makhortova NR, Hayhurst M, Cerqueira A, Sinor-Anderson AD, Zhao WN, Heiser PW, Arvanites AC, Davidow LS, Waldon ZO, Steen JA, Lam K, Ngo HD, Rubin LL. Makhortova NR, et al. Among authors: heiser pw. Nat Chem Biol. 2011 Jun 19;7(8):544-52. doi: 10.1038/nchembio.595. Nat Chem Biol. 2011. PMID: 21685895 Free PMC article.
miRNA malfunction causes spinal motor neuron disease.
Haramati S, Chapnik E, Sztainberg Y, Eilam R, Zwang R, Gershoni N, McGlinn E, Heiser PW, Wills AM, Wirguin I, Rubin LL, Misawa H, Tabin CJ, Brown R Jr, Chen A, Hornstein E. Haramati S, et al. Among authors: heiser pw. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13111-6. doi: 10.1073/pnas.1006151107. Epub 2010 Jun 29. Proc Natl Acad Sci U S A. 2010. PMID: 20616011 Free PMC article.
17 results