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Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4.
Morén A, Itoh S, Moustakas A, Dijke P, Heldin CH. Morén A, et al. Among authors: heldin ch. Oncogene. 2000 Sep 7;19(38):4396-404. doi: 10.1038/sj.onc.1203798. Oncogene. 2000. PMID: 10980615
Smad2 suppresses the growth of Mv1Lu cells subcutaneously inoculated in mice.
Sjöblom T, Yakymovych I, Heldin CH, Ostman A, Souchelnytskyi S. Sjöblom T, et al. Among authors: heldin ch. Eur J Cancer. 2004 Jan;40(2):267-74. doi: 10.1016/j.ejca.2003.08.016. Eur J Cancer. 2004. PMID: 14728942
Genome-wide mechanisms of Smad binding.
Morikawa M, Koinuma D, Miyazono K, Heldin CH. Morikawa M, et al. Among authors: heldin ch. Oncogene. 2013 Mar 28;32(13):1609-15. doi: 10.1038/onc.2012.191. Epub 2012 May 21. Oncogene. 2013. PMID: 22614010 Free PMC article. Review.
Snail depletes the tumorigenic potential of glioblastoma.
Savary K, Caglayan D, Caja L, Tzavlaki K, Bin Nayeem S, Bergström T, Jiang Y, Uhrbom L, Forsberg-Nilsson K, Westermark B, Heldin CH, Ferletta M, Moustakas A. Savary K, et al. Among authors: heldin ch. Oncogene. 2013 Nov 21;32(47):5409-20. doi: 10.1038/onc.2013.67. Epub 2013 Mar 25. Oncogene. 2013. PMID: 23524585 Free PMC article.
Efficient TGFβ-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2.
Porsch H, Bernert B, Mehić M, Theocharis AD, Heldin CH, Heldin P. Porsch H, et al. Among authors: heldin ch, heldin p. Oncogene. 2013 Sep 12;32(37):4355-65. doi: 10.1038/onc.2012.475. Epub 2012 Oct 29. Oncogene. 2013. PMID: 23108409 Free PMC article.
Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion.
Sundqvist A, Zieba A, Vasilaki E, Herrera Hidalgo C, Söderberg O, Koinuma D, Miyazono K, Heldin CH, Landegren U, Ten Dijke P, van Dam H. Sundqvist A, et al. Among authors: heldin ch. Oncogene. 2013 Aug 1;32(31):3606-15. doi: 10.1038/onc.2012.370. Epub 2012 Aug 27. Oncogene. 2013. PMID: 22926518
Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V.
Schmees C, Villaseñor R, Zheng W, Ma H, Zerial M, Heldin CH, Hellberg C. Schmees C, et al. Among authors: heldin ch. Mol Biol Cell. 2012 Jul;23(13):2571-82. doi: 10.1091/mbc.E11-04-0317. Epub 2012 May 9. Mol Biol Cell. 2012. PMID: 22573884 Free PMC article.
Characterization of an imatinib-sensitive subset of high-grade human glioma cultures.
Hägerstrand D, Hesselager G, Achterberg S, Wickenberg Bolin U, Kowanetz M, Kastemar M, Heldin CH, Isaksson A, Nistér M, Ostman A. Hägerstrand D, et al. Among authors: heldin ch. Oncogene. 2006 Aug 10;25(35):4913-22. doi: 10.1038/sj.onc.1209497. Epub 2006 Mar 20. Oncogene. 2006. PMID: 16547494
Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads.
Itoh F, Asao H, Sugamura K, Heldin CH, ten Dijke P, Itoh S. Itoh F, et al. Among authors: heldin ch. EMBO J. 2001 Aug 1;20(15):4132-42. doi: 10.1093/emboj/20.15.4132. EMBO J. 2001. PMID: 11483516 Free PMC article.
TGF-beta signaling by Smad proteins.
Miyazono K, ten Dijke P, Heldin CH. Miyazono K, et al. Among authors: heldin ch. Adv Immunol. 2000;75:115-57. doi: 10.1016/s0065-2776(00)75003-6. Adv Immunol. 2000. PMID: 10879283 Review.
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