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High interstitial fluid pressure - an obstacle in cancer therapy.
Heldin CH, Rubin K, Pietras K, Ostman A. Heldin CH, et al. Nat Rev Cancer. 2004 Oct;4(10):806-13. doi: 10.1038/nrc1456. Nat Rev Cancer. 2004. PMID: 15510161 Review.
New members of the platelet-derived growth factor family of mitogens.
Heldin CH, Eriksson U, Ostman A. Heldin CH, et al. Arch Biochem Biophys. 2002 Feb 15;398(2):284-90. doi: 10.1006/abbi.2001.2707. Arch Biochem Biophys. 2002. PMID: 11831861 Review. No abstract available.
Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair.
Kanamoto T, Hellman U, Heldin CH, Souchelnytskyi S. Kanamoto T, et al. Among authors: heldin ch. EMBO J. 2002 Mar 1;21(5):1219-30. doi: 10.1093/emboj/21.5.1219. EMBO J. 2002. PMID: 11867550 Free PMC article.
SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor.
Ekman S, Kallin A, Engström U, Heldin CH, Rönnstrand L. Ekman S, et al. Among authors: heldin ch. Oncogene. 2002 Mar 14;21(12):1870-5. doi: 10.1038/sj.onc.1205210. Oncogene. 2002. PMID: 11896619
Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA.
Edlund S, Landström M, Heldin CH, Aspenström P. Edlund S, et al. Among authors: heldin ch. Mol Biol Cell. 2002 Mar;13(3):902-14. doi: 10.1091/mbc.01-08-0398. Mol Biol Cell. 2002. PMID: 11907271 Free PMC article.
Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation.
Moustakas A, Pardali K, Gaal A, Heldin CH. Moustakas A, et al. Among authors: heldin ch. Immunol Lett. 2002 Jun 3;82(1-2):85-91. doi: 10.1016/s0165-2478(02)00023-8. Immunol Lett. 2002. PMID: 12008039 Review.
From mono- to oligo-Smads: the heart of the matter in TGF-beta signal transduction.
Moustakas A, Heldin CH. Moustakas A, et al. Among authors: heldin ch. Genes Dev. 2002 Aug 1;16(15):1867-71. doi: 10.1101/gad.1016802. Genes Dev. 2002. PMID: 12154118 No abstract available.
BRCA2 and Smad3 synergize in regulation of gene transcription.
Preobrazhenska O, Yakymovych M, Kanamoto T, Yakymovych I, Stoika R, Heldin CH, Souchelnytskyi S. Preobrazhenska O, et al. Among authors: heldin ch. Oncogene. 2002 Aug 15;21(36):5660-4. doi: 10.1038/sj.onc.1205732. Oncogene. 2002. PMID: 12165866
TGF-beta signaling from a three-dimensional perspective: insight into selection of partners.
Souchelnytskyi S, Moustakas A, Heldin CH. Souchelnytskyi S, et al. Among authors: heldin ch. Trends Cell Biol. 2002 Jul;12(7):304-7. doi: 10.1016/s0962-8924(02)02300-0. Trends Cell Biol. 2002. PMID: 12185845
Inhibition of transforming growth factor-beta signaling by low molecular weight compounds interfering with ATP- or substrate-binding sites of the TGF beta type I receptor kinase.
Yakymovych I, Engström U, Grimsby S, Heldin CH, Souchelnytskyi S. Yakymovych I, et al. Among authors: heldin ch. Biochemistry. 2002 Sep 10;41(36):11000-7. doi: 10.1021/bi025936u. Biochemistry. 2002. PMID: 12206672
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