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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling.
Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P. Nakao A, et al. Nature. 1997 Oct 9;389(6651):631-5. doi: 10.1038/39369. Nature. 1997. PMID: 9335507
Differential effects of TGF-beta1 on telomerase activity in thyroid carcinoma cell lines.
Lindkvist A, Franzén A, Ren ZP, Heldin NE, Paulsson-Karlsson Y. Lindkvist A, et al. Biochem Biophys Res Commun. 2005 Dec 23;338(3):1625-33. doi: 10.1016/j.bbrc.2005.10.131. Epub 2005 Nov 2. Biochem Biophys Res Commun. 2005. PMID: 16288728
Inhibition of TGF-beta modulates macrophages and vessel maturation in parallel to a lowering of interstitial fluid pressure in experimental carcinoma.
Salnikov AV, Roswall P, Sundberg C, Gardner H, Heldin NE, Rubin K. Salnikov AV, et al. Lab Invest. 2005 Apr;85(4):512-21. doi: 10.1038/labinvest.3700252. Lab Invest. 2005. PMID: 15711566
Interference with TGF-beta1 and -beta3 in tumor stroma lowers tumor interstitial fluid pressure independently of growth in experimental carcinoma.
Lammerts E, Roswall P, Sundberg C, Gotwals PJ, Koteliansky VE, Reed RK, Heldin NE, Rubin K. Lammerts E, et al. Int J Cancer. 2002 Dec 10;102(5):453-62. doi: 10.1002/ijc.10722. Int J Cancer. 2002. PMID: 12432546
Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3.
Edlund S, Bu S, Schuster N, Aspenström P, Heuchel R, Heldin NE, ten Dijke P, Heldin CH, Landström M. Edlund S, et al. Mol Biol Cell. 2003 Feb;14(2):529-44. doi: 10.1091/mbc.02-03-0037. Mol Biol Cell. 2003. PMID: 12589052 Free PMC article.
Hyaluronan content in experimental carcinoma is not correlated to interstitial fluid pressure.
Jacobson A, Salnikov A, Lammerts E, Roswall P, Sundberg C, Heldin P, Rubin K, Heldin NE. Jacobson A, et al. Biochem Biophys Res Commun. 2003 Jun 13;305(4):1017-23. doi: 10.1016/s0006-291x(03)00872-6. Biochem Biophys Res Commun. 2003. PMID: 12767932
Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors.
Wensman H, Heldin NE, Pejler G, Hellmén E. Wensman H, et al. Among authors: heldin ne. PLoS One. 2009 Sep 22;4(9):e7133. doi: 10.1371/journal.pone.0007133. PLoS One. 2009. PMID: 19771160 Free PMC article.
Mechanisms for 2-methoxyestradiol-induced apoptosis of prostate cancer cells.
Bu S, Blaukat A, Fu X, Heldin NE, Landström M. Bu S, et al. FEBS Lett. 2002 Nov 6;531(2):141-51. doi: 10.1016/s0014-5793(02)03478-6. FEBS Lett. 2002. PMID: 12417302
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