Helfrich BA - Search Results

1

Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.

Ware KE, Marshall ME, Heasley LR, Marek L, Hinz TK, Hercule P, Helfrich BA, Doebele RC, Heasley LE. Ware KE, et al. Among authors: helfrich ba. PLoS One. 2010 Nov 29;5(11):e14117. doi: 10.1371/journal.pone.0014117. PLoS One. 2010. PMID: 21152424 Free PMC article.

2

Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells.

Marek L, Ware KE, Fritzsche A, Hercule P, Helton WR, Smith JE, McDermott LA, Coldren CD, Nemenoff RA, Merrick DT, Helfrich BA, Bunn PA Jr, Heasley LE. Marek L, et al. Among authors: helfrich ba. Mol Pharmacol. 2009 Jan;75(1):196-207. doi: 10.1124/mol.108.049544. Epub 2008 Oct 10. Mol Pharmacol. 2009. PMID: 18849352 Free PMC article.

3

FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.

Wynes MW, Hinz TK, Gao D, Martini M, Marek LA, Ware KE, Edwards MG, Böhm D, Perner S, Helfrich BA, Dziadziuszko R, Jassem J, Wojtylak S, Sejda A, Gozgit JM, Bunn PA Jr, Camidge DR, Tan AC, Hirsch FR, Heasley LE. Wynes MW, et al. Among authors: helfrich ba. Clin Cancer Res. 2014 Jun 15;20(12):3299-309. doi: 10.1158/1078-0432.CCR-13-3060. Epub 2014 Apr 25. Clin Cancer Res. 2014. PMID: 24771645 Free PMC article.

4

A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop.

Ware KE, Hinz TK, Kleczko E, Singleton KR, Marek LA, Helfrich BA, Cummings CT, Graham DK, Astling D, Tan AC, Heasley LE. Ware KE, et al. Among authors: helfrich ba. Oncogenesis. 2013 Mar 25;2(3):e39. doi: 10.1038/oncsis.2013.4. Oncogenesis. 2013. PMID: 23552882 Free PMC article.

5

PTTG1 Levels Are Predictive of Saracatinib Sensitivity in Ovarian Cancer Cell Lines.

Nakachi I, Helfrich BA, Spillman MA, Mickler EA, Olson CJ, Rice JL, Coldren CD, Heasley LE, Geraci MW, Stearman RS. Nakachi I, et al. Among authors: helfrich ba. Clin Transl Sci. 2016 Dec;9(6):293-301. doi: 10.1111/cts.12413. Epub 2016 Oct 20. Clin Transl Sci. 2016. PMID: 27766744 Free PMC article.

6

Expression of catalytically inactive phospholipase Cbeta disrupts phospholipase Cbeta and mitogen-activated protein kinase signaling and inhibits small cell lung cancer growth.

Beekman A, Helfrich B, Bunn PA Jr, Heasley LE. Beekman A, et al. Cancer Res. 1998 Mar 1;58(5):910-3. Cancer Res. 1998. PMID: 9500449

7

Native and rearranged ALK copy number and rearranged cell count in non-small cell lung cancer: implications for ALK inhibitor therapy.

Camidge DR, Skokan M, Kiatsimkul P, Helfrich B, Lu X, Barón AE, Schulte N, Maxson D, Aisner DL, Franklin WA, Doebele RC, Varella-Garcia M. Camidge DR, et al. Cancer. 2013 Nov 15;119(22):3968-75. doi: 10.1002/cncr.28311. Epub 2013 Sep 10. Cancer. 2013. PMID: 24022839 Free PMC article.

8

Discordant signal transduction and growth inhibition of small cell lung carcinomas induced by expression of GTPase-deficient G alpha 16.

Heasley LE, Zamarripa J, Storey B, Helfrich B, Mitchell FM, Bunn PA Jr, Johnson GL. Heasley LE, et al. J Biol Chem. 1996 Jan 5;271(1):349-54. doi: 10.1074/jbc.271.1.349. J Biol Chem. 1996. PMID: 8550585 Free article.

9

Synergistic effects of new chemopreventive agents and conventional cytotoxic agents against human lung cancer cell lines.

Soriano AF, Helfrich B, Chan DC, Heasley LE, Bunn PA Jr, Chou TC. Soriano AF, et al. Cancer Res. 1999 Dec 15;59(24):6178-84. Cancer Res. 1999. PMID: 10626810

10

Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma.

Frederick BA, Helfrich BA, Coldren CD, Zheng D, Chan D, Bunn PA Jr, Raben D. Frederick BA, et al. Among authors: helfrich ba. Mol Cancer Ther. 2007 Jun;6(6):1683-91. doi: 10.1158/1535-7163.MCT-07-0138. Epub 2007 May 31. Mol Cancer Ther. 2007. PMID: 17541031

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