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Fibrin as a delivery vehicle for active macrophage activator lipoprotein-2 peptide: in vitro studies.
Cole M, Cox S, Inman E, Chan C, Mana M, Helgerson S, Tawil B. Cole M, et al. Among authors: helgerson s. Wound Repair Regen. 2007 Jul-Aug;15(4):521-9. doi: 10.1111/j.1524-475X.2007.00260.x. Wound Repair Regen. 2007. PMID: 17650096
Next, we examined MALP-2's effect on the human monocyte cell line when it is mixed with fibrin. Monocytes seeded on three-dimensional fibrin containing MALP-2 secreted more cytokines such as interleukin-6, tumor necrosis factor-alpha, and chemoattractants such as macrophag …
Next, we examined MALP-2's effect on the human monocyte cell line when it is mixed with fibrin. Monocytes seeded on three-dimensional …
Sustained (rh)VEGF(165) release from a sprayed fibrin biomatrix induces angiogenesis, up-regulation of endogenous VEGF-R2, and reduces ischemic flap necrosis.
Mittermayr R, Morton T, Hofmann M, Helgerson S, van Griensven M, Redl H. Mittermayr R, et al. Among authors: helgerson s. Wound Repair Regen. 2008 Jul-Aug;16(4):542-50. doi: 10.1111/j.1524-475X.2008.00391.x. Wound Repair Regen. 2008. PMID: 18494746
Controlled release of bioactive transforming growth factor beta-1 from fibrin gels in vitro.
Catelas I, Dwyer JF, Helgerson S. Catelas I, et al. Among authors: helgerson s. Tissue Eng Part C Methods. 2008 Jun;14(2):119-28. doi: 10.1089/ten.tec.2007.0262. Tissue Eng Part C Methods. 2008. PMID: 18544028
Human mesenchymal stem cell proliferation and osteogenic differentiation in fibrin gels in vitro.
Catelas I, Sese N, Wu BM, Dunn JC, Helgerson S, Tawil B. Catelas I, et al. Among authors: helgerson s. Tissue Eng. 2006 Aug;12(8):2385-96. doi: 10.1089/ten.2006.12.2385. Tissue Eng. 2006. PMID: 16968177
Fibrin-based biomaterials to deliver human growth factors.
Wong C, Inman E, Spaethe R, Helgerson S. Wong C, et al. Among authors: helgerson s. Thromb Haemost. 2003 Mar;89(3):573-82. Thromb Haemost. 2003. PMID: 12624643
Isolation and characterization of thrombin-activated human factor VIII.
Curtis JE, Helgerson SL, Parker ET, Lollar P. Curtis JE, et al. Among authors: helgerson sl. J Biol Chem. 1994 Feb 25;269(8):6246-51. J Biol Chem. 1994. PMID: 8119969
Inhibition of human factor VIIIa by anti-A2 subunit antibodies.
Lollar P, Parker ET, Curtis JE, Helgerson SL, Hoyer LW, Scott ME, Scandella D. Lollar P, et al. Among authors: helgerson sl. J Clin Invest. 1994 Jun;93(6):2497-504. doi: 10.1172/JCI117259. J Clin Invest. 1994. PMID: 8200986 Free PMC article.
Analysis of activation-induced conformational changes in p47phox using tryptophan fluorescence spectroscopy.
Swain SD, Helgerson SL, Davis AR, Nelson LK, Quinn MT. Swain SD, et al. Among authors: helgerson sl. J Biol Chem. 1997 Nov 21;272(47):29502-10. doi: 10.1074/jbc.272.47.29502. J Biol Chem. 1997. PMID: 9368011
NMR constrained solution structures for laminin peptide 11. Analogs define structural requirements for inhibition of tumor cell invasion of basement membrane matrix.
Ostheimer GJ, Starkey JR, Lambert CG, Helgerson SL, Dratz EA. Ostheimer GJ, et al. Among authors: helgerson sl. J Biol Chem. 1992 Dec 15;267(35):25120-8. J Biol Chem. 1992. PMID: 1460013
Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa.
Parise LV, Helgerson SL, Steiner B, Nannizzi L, Phillips DR. Parise LV, et al. Among authors: helgerson sl. J Biol Chem. 1987 Sep 15;262(26):12597-602. J Biol Chem. 1987. PMID: 2957377
Finally, the decapeptide or RGDS decreased the sedimentation coefficient of GP IIb-IIIa from 8.5 to 7.7 or 7.4 S, respectively, whereas RGES had a minimal effect. This decrease was accompanied by an increase in the Stoke's radius from 74 to 82 A with RGDS or 85 A wi …
Finally, the decapeptide or RGDS decreased the sedimentation coefficient of GP IIb-IIIa from 8.5 to 7.7 or 7.4 S, respectively, where …
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