Hellberg K - Search Results

1

AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy.

Hung CM, Lombardo PS, Malik N, Brun SN, Hellberg K, Van Nostrand JL, Garcia D, Baumgart J, Diffenderfer K, Asara JM, Shaw RJ. Hung CM, et al. Among authors: hellberg k. Sci Adv. 2021 Apr 7;7(15):eabg4544. doi: 10.1126/sciadv.abg4544. Print 2021 Apr. Sci Adv. 2021. PMID: 33827825 Free PMC article.

2

Pulsed Azidohomoalanine Labeling in Mammals (PALM) Detects Changes in Liver-Specific LKB1 Knockout Mice.

McClatchy DB, Ma Y, Liu C, Stein BD, Martínez-Bartolomé S, Vasquez D, Hellberg K, Shaw RJ, Yates JR 3rd. McClatchy DB, et al. Among authors: hellberg k. J Proteome Res. 2015 Nov 6;14(11):4815-22. doi: 10.1021/acs.jproteome.5b00653. Epub 2015 Oct 26. J Proteome Res. 2015. PMID: 26445171 Free PMC article.

3

Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.

Toyama EQ, Herzig S, Courchet J, Lewis TL Jr, Losón OC, Hellberg K, Young NP, Chen H, Polleux F, Chan DC, Shaw RJ. Toyama EQ, et al. Among authors: hellberg k. Science. 2016 Jan 15;351(6270):275-281. doi: 10.1126/science.aab4138. Science. 2016. PMID: 26816379 Free PMC article.

4

Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex.

Howell JJ, Hellberg K, Turner M, Talbott G, Kolar MJ, Ross DS, Hoxhaj G, Saghatelian A, Shaw RJ, Manning BD. Howell JJ, et al. Among authors: hellberg k. Cell Metab. 2017 Feb 7;25(2):463-471. doi: 10.1016/j.cmet.2016.12.009. Epub 2017 Jan 12. Cell Metab. 2017. PMID: 28089566 Free PMC article.

5

Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD.

Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur MG, Lin T, Shokhirev MN, Pinto AFM, Ross DS, Saghatelian A, Panda S, Dow LE, Metallo CM, Shaw RJ. Garcia D, et al. Among authors: hellberg k. Cell Rep. 2019 Jan 2;26(1):192-208.e6. doi: 10.1016/j.celrep.2018.12.036. Cell Rep. 2019. PMID: 30605676 Free PMC article.

6

Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks.

Stein BD, Calzolari D, Hellberg K, Hu YS, He L, Hung CM, Toyama EQ, Ross DS, Lillemeier BF, Cantley LC, Yates JR 3rd, Shaw RJ. Stein BD, et al. Among authors: hellberg k. Cell Rep. 2019 Dec 3;29(10):3331-3348.e7. doi: 10.1016/j.celrep.2019.10.117. Cell Rep. 2019. PMID: 31801093 Free PMC article.

7

AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation.

Van Nostrand JL, Hellberg K, Luo EC, Van Nostrand EL, Dayn A, Yu J, Shokhirev MN, Dayn Y, Yeo GW, Shaw RJ. Van Nostrand JL, et al. Among authors: hellberg k. Genes Dev. 2020 Oct 1;34(19-20):1330-1344. doi: 10.1101/gad.339895.120. Epub 2020 Sep 10. Genes Dev. 2020. PMID: 32912901 Free PMC article.

8

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1.

Malik N, Ferreira BI, Hollstein PE, Curtis SD, Trefts E, Weiser Novak S, Yu J, Gilson R, Hellberg K, Fang L, Sheridan A, Hah N, Shadel GS, Manor U, Shaw RJ. Malik N, et al. Among authors: hellberg k. Science. 2023 Apr 21;380(6642):eabj5559. doi: 10.1126/science.abj5559. Epub 2023 Apr 21. Science. 2023. PMID: 37079666 Free PMC article.

9

X-ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4-hydroxy-2-nonenal.

Hellberg K, Grimsrud PA, Kruse AC, Banaszak LJ, Ohlendorf DH, Bernlohr DA. Hellberg K, et al. Protein Sci. 2010 Aug;19(8):1480-9. doi: 10.1002/pro.427. Protein Sci. 2010. PMID: 20509169 Free PMC article.

10

Fatty acids induce leukotriene C4 synthesis in macrophages in a fatty acid binding protein-dependent manner.

Long EK, Hellberg K, Foncea R, Hertzel AV, Suttles J, Bernlohr DA. Long EK, et al. Among authors: hellberg k. Biochim Biophys Acta. 2013 Jul;1831(7):1199-207. Biochim Biophys Acta. 2013. PMID: 24046860

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