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Page 1
Helleborus.
Adams E. Adams E. Homoeopath Physician. 1888 Aug;8(8):421-422. Homoeopath Physician. 1888. PMID: 37135475 Free PMC article. No abstract available.
Pharmacognostical and Phytochemical Studies of Helleborus niger L Root.
Kumar VK, Lalitha KG. Kumar VK, et al. Anc Sci Life. 2017 Jan-Mar;36(3):151-158. doi: 10.4103/asl.ASL_57_16. Anc Sci Life. 2017. PMID: 28867859 Free PMC article.
BACKGROUND: Helleborus niger L (Ranunculaceae) is used Ayurvedic and Unani systems and other herbal medicine systems. The roots of H. niger have a good medicinal value. AIMS: To conduct a pharmacognostical and phytochemical study of H. niger. ...
BACKGROUND: Helleborus niger L (Ranunculaceae) is used Ayurvedic and Unani systems and other herbal medicine systems. The root …
Subcutaneous application of Helleborus niger 12x in older patients with dementia-a retrospective cohort study.
Vagedes J, Hagen A, Islam MOA, Sobh M, Vagedes K, Szőke H, Kohl M, Wilkens J. Vagedes J, et al. Front Public Health. 2026 Mar 25;14:1758447. doi: 10.3389/fpubh.2026.1758447. eCollection 2026. Front Public Health. 2026. PMID: 41960405 Free PMC article.
In a German hospital specializing in geriatric patients, an association between the subcutaneous application of Helleborus niger 12x and changes in dementia was observed. METHODS: Retrospective study on the effect of subcutaneous application of Helleborus …
In a German hospital specializing in geriatric patients, an association between the subcutaneous application of Helleborus niger …
Bufadienolides and ecdysteroids from the whole plants of Helleborus niger and their cytotoxicity.
Yokosuka A, Inomata M, Yoshizawa Y, Iguchi T, Mimaki Y. Yokosuka A, et al. J Nat Med. 2021 Mar;75(2):393-402. doi: 10.1007/s11418-021-01481-6. Epub 2021 Jan 27. J Nat Med. 2021. PMID: 33502658
A new bufadienolide (1), two new bufadienolide glycosides (2 and 3), a new ecdysteroid (4), and four known compounds (5-8), were isolated from the whole plants of Helleborus niger L. (Ranunculaceae). The structures of the new compounds (1-4) were determined by spect …
A new bufadienolide (1), two new bufadienolide glycosides (2 and 3), a new ecdysteroid (4), and four known compounds (5-8), were isolated fr …
Effects of a phytopreparation from Helleborus niger on immunocompetent cells in vitro.
Büssing A, Schweizer K. Büssing A, et al. J Ethnopharmacol. 1998 Jan;59(3):139-46. doi: 10.1016/s0378-8741(97)00114-1. J Ethnopharmacol. 1998. PMID: 9507897
In Germany, Helleborus niger is used in homeopathy and as an adjuvant therapy in the treatment of tumor patients in anthroposophical medicine. In vitro application of an aqueous extract from Helleborus niger resulted in a slight induction of sister chr …
In Germany, Helleborus niger is used in homeopathy and as an adjuvant therapy in the treatment of tumor patients in anthroposo …
[Chemical constituents of Helleborus thibetanus].
Li YZ, Zhang DD, Huang WL, Jiang Y, Zhang HW, Deng C, Wang W, Liu JL, Song XM. Li YZ, et al. Zhongguo Zhong Yao Za Zhi. 2023 Dec;48(23):6408-6413. doi: 10.19540/j.cnki.cjcmm.20230906.201. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 38211998 Chinese.
The chemical constituents of Helleborus thibetanus were isolated and purified by silica gel column chromatography, Sephadex LH-20 gel column chromatography, and semi-preparative RP-HPLC, and the structures of all compounds were identified by modern spectrographic technolog …
The chemical constituents of Helleborus thibetanus were isolated and purified by silica gel column chromatography, Sephadex LH-20 gel …
Steroidal constituents in the whole plants of Helleborus niger and their cytotoxic activity in vitro.
Yoshizawa Y, Yokosuka A, Inomata M, Iguchi T, Mimaki Y. Yoshizawa Y, et al. Phytochemistry. 2025 Jan;229:114272. doi: 10.1016/j.phytochem.2024.114272. Epub 2024 Sep 12. Phytochemistry. 2025. PMID: 39260588
Phytochemical investigation of the whole plants of Helleborus niger L. (Ranunculaceae) resulted in the isolation of five undescribed compounds, including one bufadienolide (1), two bufadienolide rhamnosides (2 and 3), and two ecdysteroids (12 and 13), along with eig …
Phytochemical investigation of the whole plants of Helleborus niger L. (Ranunculaceae) resulted in the isolation of five undes …
Differential cytotoxic properties of Helleborus niger L. on tumour and immunocompetent cells.
Schink M, Garcia-Käufer M, Bertrams J, Duckstein SM, Müller MB, Huber R, Stintzing FC, Gründemann C. Schink M, et al. J Ethnopharmacol. 2015 Jan 15;159:129-36. doi: 10.1016/j.jep.2014.11.003. Epub 2014 Nov 13. J Ethnopharmacol. 2015. PMID: 25446603
ETHNOPHARMACOLOGICAL RELEVANCE: In Romanian folk medicine, Helleborus niger L. is used for the treatment of rheumatoid arthritis or viral infections and in complementary therapy, especially in anthroposophic medicine (AM), where the plant is administered as an adjuv …
ETHNOPHARMACOLOGICAL RELEVANCE: In Romanian folk medicine, Helleborus niger L. is used for the treatment of rheumatoid arthrit …
Genus Helleborus: a comprehensive review of phytochemistry, pharmacology and clinical applications.
Li S, Chen X, Tang J, Zhang D, Jiang Y, Zhang H, Song X, Wang W, Li Y. Li S, et al. Nat Prod Res. 2025 Feb;39(4):888-904. doi: 10.1080/14786419.2024.2317880. Epub 2024 Feb 19. Nat Prod Res. 2025. PMID: 38372230 Review.
The genus Helleborus belongs to the Ranunculaceae family, distributed in southeastern Europe and western Asia. ...This article reviews the botany, phytochemistry, pharmacological effects and clinical applications of the genus Helleborus. Hopefully, it will provide a …
The genus Helleborus belongs to the Ranunculaceae family, distributed in southeastern Europe and western Asia. ...This article review …
213 results