Heller NM - Search Results

1

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC. LaPorte SL, et al. Among authors: heller nm. Cell. 2008 Jan 25;132(2):259-72. doi: 10.1016/j.cell.2007.12.030. Cell. 2008. PMID: 18243101 Free PMC article.

2

Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages.

Heller NM, Qi X, Junttila IS, Shirey KA, Vogel SN, Paul WE, Keegan AD. Heller NM, et al. Sci Signal. 2008 Dec 23;1(51):ra17. doi: 10.1126/scisignal.1164795. Sci Signal. 2008. PMID: 19109239 Free PMC article.

3

An atopy-associated polymorphism in the ectodomain of the IL-4R(alpha) chain (V50) regulates the persistence of STAT6 phosphorylation.

Ford AQ, Heller NM, Stephenson L, Boothby MR, Keegan AD. Ford AQ, et al. Among authors: heller nm. J Immunol. 2009 Aug 1;183(3):1607-16. doi: 10.4049/jimmunol.0803266. Epub 2009 Jul 10. J Immunol. 2009. PMID: 19592641 Free PMC article.

4

IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro.

Heller NM, Gwinn WM, Donnelly RP, Constant SL, Keegan AD. Heller NM, et al. PLoS One. 2012;7(6):e39673. doi: 10.1371/journal.pone.0039673. Epub 2012 Jun 28. PLoS One. 2012. PMID: 22761864 Free PMC article.

5

Regulation of inflammation by interleukin-4: a review of "alternatives".

Luzina IG, Keegan AD, Heller NM, Rook GA, Shea-Donohue T, Atamas SP. Luzina IG, et al. Among authors: heller nm. J Leukoc Biol. 2012 Oct;92(4):753-64. doi: 10.1189/jlb.0412214. Epub 2012 Jul 10. J Leukoc Biol. 2012. PMID: 22782966 Free PMC article. Review.

6

The extracellular and transmembrane domains of the γC and interleukin (IL)-13 receptor α1 chains, not their cytoplasmic domains, dictate the nature of signaling responses to IL-4 and IL-13.

Heller NM, Qi X, Gesbert F, Keegan AD. Heller NM, et al. J Biol Chem. 2012 Sep 14;287(38):31948-61. doi: 10.1074/jbc.M112.348896. Epub 2012 Jul 24. J Biol Chem. 2012. PMID: 22829596 Free PMC article.

7

IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View.

Keegan AD, Zamorano J, Keselman A, Heller NM. Keegan AD, et al. Among authors: heller nm. Front Immunol. 2018 May 15;9:1037. doi: 10.3389/fimmu.2018.01037. eCollection 2018. Front Immunol. 2018. PMID: 29868002 Free PMC article. Review.

8

Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds.

Yang H, Ulge UY, Quijano-Rubio A, Bernstein ZJ, Maestas DR, Chun JH, Wang W, Lin JX, Jude KM, Singh S, Orcutt-Jahns BT, Li P, Mou J, Chung L, Kuo YH, Ali YH, Meyer AS, Grayson WL, Heller NM, Garcia KC, Leonard WJ, Silva DA, Elisseeff JH, Baker D, Spangler JB. Yang H, et al. Among authors: heller nm. Nat Chem Biol. 2023 Sep;19(9):1127-1137. doi: 10.1038/s41589-023-01313-6. Epub 2023 Apr 6. Nat Chem Biol. 2023. PMID: 37024727 Free PMC article.

9

Interferon-gamma inhibits STAT6 signal transduction and gene expression in human airway epithelial cells.

Heller NM, Matsukura S, Georas SN, Boothby MR, Rothman PB, Stellato C, Schleimer RP. Heller NM, et al. Am J Respir Cell Mol Biol. 2004 Nov;31(5):573-82. doi: 10.1165/rcmb.2004-0195OC. Epub 2004 Aug 5. Am J Respir Cell Mol Biol. 2004. PMID: 15297269

10

Estrogen Signaling Contributes to Sex Differences in Macrophage Polarization during Asthma.

Keselman A, Fang X, White PB, Heller NM. Keselman A, et al. Among authors: heller nm. J Immunol. 2017 Sep 1;199(5):1573-1583. doi: 10.4049/jimmunol.1601975. Epub 2017 Jul 31. J Immunol. 2017. PMID: 28760880 Free PMC article.

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