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Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen.
Ramirez-Ardila DE, Helmijr JC, Look MP, Lurkin I, Ruigrok-Ritstier K, van Laere S, Dirix L, Sweep FC, Span PN, Linn SC, Foekens JA, Sleijfer S, Berns EM, Jansen MP. Ramirez-Ardila DE, et al. Among authors: helmijr jc. Breast Cancer Res Treat. 2013 May;139(1):39-49. doi: 10.1007/s10549-013-2529-7. Epub 2013 Apr 17. Breast Cancer Res Treat. 2013. PMID: 23592373
Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen.
Jansen MP, Martens JW, Helmijr JC, Beaufort CM, van Marion R, Krol NM, Monkhorst K, Trapman-Jansen AM, Meijer-van Gelder ME, Weerts MJ, Ramirez-Ardila DE, Dubbink HJ, Foekens JA, Sleijfer S, Berns EM. Jansen MP, et al. Among authors: helmijr jc. Oncotarget. 2016 Jul 12;7(28):43412-43418. doi: 10.18632/oncotarget.9727. Oncotarget. 2016. PMID: 27270325 Free PMC article.
Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases.
Beije N, Helmijr JC, Weerts MJA, Beaufort CM, Wiggin M, Marziali A, Verhoef C, Sleijfer S, Jansen MPHM, Martens JWM. Beije N, et al. Among authors: helmijr jc. Mol Oncol. 2016 Dec;10(10):1575-1584. doi: 10.1016/j.molonc.2016.10.001. Mol Oncol. 2016. PMID: 28949453 Free PMC article.
High-throughput isolation of circulating tumor DNA: a comparison of automated platforms.
van Dessel LF, Vitale SR, Helmijr JCA, Wilting SM, van der Vlugt-Daane M, Oomen-de Hoop E, Sleijfer S, Martens JWM, Jansen MPHM, Lolkema MP. van Dessel LF, et al. Among authors: helmijr jca. Mol Oncol. 2019 Feb;13(2):392-402. doi: 10.1002/1878-0261.12415. Epub 2018 Dec 22. Mol Oncol. 2019. PMID: 30516338 Free PMC article.
TP53 Mutations in Serum Circulating Cell-Free Tumor DNA As Longitudinal Biomarker for High-Grade Serous Ovarian Cancer.
Vitale SR, Groenendijk FH, van Marion R, Beaufort CM, Helmijr JC, Dubbink HJ, Dinjens WNM, Ewing-Graham PC, Smolders R, van Doorn HC, Boere IA, Berns EMJJ, Helleman J, Jansen MPHM. Vitale SR, et al. Among authors: helmijr jc. Biomolecules. 2020 Mar 7;10(3):415. doi: 10.3390/biom10030415. Biomolecules. 2020. PMID: 32156073 Free PMC article. Clinical Trial.
Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients.
Valle-Inclan JE, Stangl C, de Jong AC, van Dessel LF, van Roosmalen MJ, Helmijr JCA, Renkens I, Janssen R, de Blank S, de Witte CJ, Martens JWM, Jansen MPHM, Lolkema MP, Kloosterman WP. Valle-Inclan JE, et al. Among authors: helmijr jca. Genome Med. 2021 May 18;13(1):86. doi: 10.1186/s13073-021-00899-7. Genome Med. 2021. PMID: 34006333 Free PMC article.
15 results