Heltemes-Harris LM - Search Results

1

Combining nilotinib and PD-L1 blockade reverses CD4+ T-cell dysfunction and prevents relapse in acute B-cell leukemia.

Tracy SI, Venkatesh H, Hekim C, Heltemes-Harris LM, Knutson TP, Bachanova V, Farrar MA. Tracy SI, et al. Among authors: heltemes harris lm. Blood. 2022 Jul 28;140(4):335-348. doi: 10.1182/blood.2021015341. Blood. 2022. PMID: 35275990 Free PMC article.

2

The role of STAT5 in the development, function, and transformation of B and T lymphocytes.

Heltemes-Harris LM, Willette MJ, Vang KB, Farrar MA. Heltemes-Harris LM, et al. Ann N Y Acad Sci. 2011 Jan;1217:18-31. doi: 10.1111/j.1749-6632.2010.05907.x. Ann N Y Acad Sci. 2011. PMID: 21276004 Review.

3

Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia.

Heltemes-Harris LM, Willette MJ, Ramsey LB, Qiu YH, Neeley ES, Zhang N, Thomas DA, Koeuth T, Baechler EC, Kornblau SM, Farrar MA. Heltemes-Harris LM, et al. J Exp Med. 2011 Jun 6;208(6):1135-49. doi: 10.1084/jem.20101947. Epub 2011 May 23. J Exp Med. 2011. PMID: 21606506 Free PMC article.

4

The role of STAT5 in lymphocyte development and transformation.

Heltemes-Harris LM, Farrar MA. Heltemes-Harris LM, et al. Curr Opin Immunol. 2012 Apr;24(2):146-52. doi: 10.1016/j.coi.2012.01.015. Epub 2012 Feb 16. Curr Opin Immunol. 2012. PMID: 22342169 Free PMC article. Review.

5

Constitutively active STAT5 constructs.

Heltemes-Harris LM, Farrar MA. Heltemes-Harris LM, et al. Methods Mol Biol. 2013;967:225-32. doi: 10.1007/978-1-62703-242-1_16. Methods Mol Biol. 2013. PMID: 23296733

6

Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemia.

Heltemes-Harris LM, Larson JD, Starr TK, Hubbard GK, Sarver AL, Largaespada DA, Farrar MA. Heltemes-Harris LM, et al. Oncogene. 2016 Jun 30;35(26):3454-64. doi: 10.1038/onc.2015.405. Epub 2015 Oct 26. Oncogene. 2016. PMID: 26500062 Free PMC article.

7

Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival.

Katerndahl CDS, Heltemes-Harris LM, Willette MJL, Henzler CM, Frietze S, Yang R, Schjerven H, Silverstein KAT, Ramsey LB, Hubbard G, Wells AD, Kuiper RP, Scheijen B, van Leeuwen FN, Müschen M, Kornblau SM, Farrar MA. Katerndahl CDS, et al. Among authors: heltemes harris lm. Nat Immunol. 2017 Jun;18(6):694-704. doi: 10.1038/ni.3716. Epub 2017 Apr 3. Nat Immunol. 2017. PMID: 28369050 Free PMC article.

8

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma.

Rahrmann EP, Wolf NK, Otto GM, Heltemes-Harris L, Ramsey LB, Shu J, LaRue RS, Linden MA, Rathe SK, Starr TK, Farrar MA, Moriarity BS, Largaespada DA. Rahrmann EP, et al. Mol Cancer Res. 2019 Feb;17(2):567-582. doi: 10.1158/1541-7786.MCR-18-0582. Epub 2018 Oct 24. Mol Cancer Res. 2019. PMID: 30355676

9

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.

Wong JB, Hewitt SL, Heltemes-Harris LM, Mandal M, Johnson K, Rajewsky K, Koralov SB, Clark MR, Farrar MA, Skok JA. Wong JB, et al. Among authors: heltemes harris lm. Nat Commun. 2019 Oct 18;10(1):4768. doi: 10.1038/s41467-019-12824-z. Nat Commun. 2019. PMID: 31628339 Free PMC article.

10

Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia.

Heltemes-Harris LM, Hubbard GK, LaRue RS, Munro SA, Yang R, Henzler CM, Starr TK, Sarver AL, Kornblau SM, Farrar MA. Heltemes-Harris LM, et al. Oncogene. 2021 Oct;40(43):6166-6179. doi: 10.1038/s41388-021-02012-z. Epub 2021 Sep 17. Oncogene. 2021. PMID: 34535769 Free PMC article.

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