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Hemidesmus indicus induces immunogenic death in human colorectal cancer cells.
Turrini E, Catanzaro E, Muraro MG, Governa V, Trella E, Mele V, Calcabrini C, Morroni F, Sita G, Hrelia P, Tacchini M, Fimognari C. Turrini E, et al. Oncotarget. 2018 May 11;9(36):24443-24456. doi: 10.18632/oncotarget.25325. eCollection 2018 May 11. Oncotarget. 2018. PMID: 29849952 Free PMC article.
The ability of anticancer treatments to promote the activation of tumor-reactive adaptive immune responses is emerging as a critical requirement underlying their clinical effectiveness. We investigated the ability of Hemidesmus indicus, a promising anticancer botani …
The ability of anticancer treatments to promote the activation of tumor-reactive adaptive immune responses is emerging as a critical require …
Exploring the endogenous potential of Hemidesmus indicus against breast cancer using in silico studies and quantification of 2-hydroxy-4-methoxy benzaldehyde through RP-HPLC.
Bansod AA, Ramasamy G, Nathan B, Kandhasamy R, Palaniappan M, Vichangal Pridiuldi S. Bansod AA, et al. 3 Biotech. 2021 May;11(5):235. doi: 10.1007/s13205-021-02768-x. Epub 2021 Apr 24. 3 Biotech. 2021. PMID: 33968579 Free PMC article.
Current investigation involves virtually screening of 19 protein receptors having major role in signal transduction pathway of breast cancer development against 47 compounds present in Hemidesmus indicus. ...From the current investigation, it could be surmise …
Current investigation involves virtually screening of 19 protein receptors having major role in signal transduction pathway of breast can …
Indian Sarsaparilla (Hemidesmus indicus): Recent progress in research on ethnobotany, phytochemistry and pharmacology.
Nandy S, Mukherjee A, Pandey DK, Ray P, Dey A. Nandy S, et al. J Ethnopharmacol. 2020 May 23;254:112609. doi: 10.1016/j.jep.2020.112609. Epub 2020 Jan 30. J Ethnopharmacol. 2020. PMID: 32007632 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Hemidesmus indicus (L.) R. Br. ex Schult. (Apocynaceae) is widely used in traditional medicine in the different parts of the Indian subcontinent due to the various biological activities attributed to its different parts, especially th …
ETHNOPHARMACOLOGICAL RELEVANCE: Hemidesmus indicus (L.) R. Br. ex Schult. (Apocynaceae) is widely used in traditional medicine …
In vitro anti-angiogenic effects of Hemidesmus indicus in hypoxic and normoxic conditions.
Turrini E, Ferruzzi L, Guerrini A, Gotti R, Tacchini M, Teti G, Falconi M, Hrelia P, Fimognari C. Turrini E, et al. J Ethnopharmacol. 2015 Mar 13;162:261-9. doi: 10.1016/j.jep.2014.12.010. Epub 2015 Jan 2. J Ethnopharmacol. 2015. PMID: 25560668
ETHNOPHARMACOLOGICAL RELEVANCE: The decoction of the roots of Hemidesmus indicus is widely used in the Indian traditional medicine for many purposes and poly-herbal preparations containing Hemidesmus are often used by traditional medical practitioners for the …
ETHNOPHARMACOLOGICAL RELEVANCE: The decoction of the roots of Hemidesmus indicus is widely used in the Indian traditional medi …
Hemidesmus indicus induces apoptosis as well as differentiation in a human promyelocytic leukemic cell line.
Ferruzzi L, Turrini E, Burattini S, Falcieri E, Poli F, Mandrone M, Sacchetti G, Tacchini M, Guerrini A, Gotti R, Hrelia P, Cantelli-Forti G, Fimognari C. Ferruzzi L, et al. J Ethnopharmacol. 2013 May 2;147(1):84-91. doi: 10.1016/j.jep.2013.02.009. Epub 2013 Mar 14. J Ethnopharmacol. 2013. PMID: 23500881
The aim of this study was to investigate the cytodifferentiative, cytostatic and cytotoxic potential of a decoction of Hemidesmus indicus's roots (0.31-3 mg/mL) on a human promyelocytic leukemia cell line (HL-60). MATERIALS AND METHODS: The decoction of He …
The aim of this study was to investigate the cytodifferentiative, cytostatic and cytotoxic potential of a decoction of Hemidesmus …
Mitochondrial pathway mediates the antileukemic effects of Hemidesmus indicus, a promising botanical drug.
Fimognari C, Lenzi M, Ferruzzi L, Turrini E, Scartezzini P, Poli F, Gotti R, Guerrini A, Carulli G, Ottaviano V, Cantelli-Forti G, Hrelia P. Fimognari C, et al. PLoS One. 2011;6(6):e21544. doi: 10.1371/journal.pone.0021544. Epub 2011 Jun 28. PLoS One. 2011. PMID: 21738701 Free PMC article.
The present study is designed to explore the potential antileukemic properties of Hemidesmus indicus with a view to contributing to further development of botanical drugs. Hemidesmus was submitted to an extensive in vitro preclinical evaluation. ...
The present study is designed to explore the potential antileukemic properties of Hemidesmus indicus with a view to contributi …
In Vitro Study of the Cytotoxic, Cytostatic, and Antigenotoxic Profile of Hemidesmus indicus (L.) R.Br. (Apocynaceae) Crude Drug Extract on T Lymphoblastic Cells.
Turrini E, Calcabrini C, Tacchini M, Efferth T, Sacchetti G, Guerrini A, Paganetto G, Catanzaro E, Greco G, Fimognari C. Turrini E, et al. Toxins (Basel). 2018 Feb 6;10(2):70. doi: 10.3390/toxins10020070. Toxins (Basel). 2018. PMID: 29415441 Free PMC article.
In traditional Indian medicine, the crude drug Hemidesmus indicus root-commonly known as Indian sarsaparilla-is used alone or in poly-herbal preparations for the treatment of a wide range of diseases. The present study focuses on the cancer chemopreventive an …
In traditional Indian medicine, the crude drug Hemidesmus indicus root-commonly known as Indian sarsaparilla-is used alone or …
Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus indicus R. Br.
Statti G, Marrelli M, Conforti F, Spagnoletti A, Tacchini M, Fimognari C, Brognara E, Gambari R, Sacchetti G, Guerrini A. Statti G, et al. Phytother Res. 2015 Jun;29(6):857-63. doi: 10.1002/ptr.5322. Epub 2015 Mar 6. Phytother Res. 2015. PMID: 25753739
Indian Sarsaparilla (Hemidesmus indicus R. Br.) is widely used in Indian traditional medicine. ...The antiproliferative and antioxidant properties were assayed. To test antiproliferative affects, different cancer cell lines, growing both as monolayers (CaCo2, …
Indian Sarsaparilla (Hemidesmus indicus R. Br.) is widely used in Indian traditional medicine. ...The antiproliferative and an …
Amelioration of cisplatin-induced nephrotoxicity by extracts of Hemidesmus indicus and Acorus calamus.
Sandeep D, Krishnan Nair CK. Sandeep D, et al. Pharm Biol. 2010 Mar;48(3):290-5. doi: 10.3109/13880200903116048. Pharm Biol. 2010. PMID: 20645815
Administration of commonly used anticancer drug cisplatin [cis-diamminedichloroplatinum (II)] at pharmacologically relevant concentrations (12 mg/kg body weight) resulted in severe renal toxicity as evidenced from histopathological observations and biochemical alterations in the …
Administration of commonly used anticancer drug cisplatin [cis-diamminedichloroplatinum (II)] at pharmacologically relevant concentrations ( …
Protective Effect of a Polyherbal Aqueous Extract Comprised of Nigella sativa (Seeds), Hemidesmus indicus (Roots), and Smilax glabra (Rhizome) on Bleomycin Induced Cytogenetic Damage in Human Lymphocytes.
Galhena BP, Samarakoon SSR, Thabrew MI, Paul SFD, Perumal V, Mani C. Galhena BP, et al. Biomed Res Int. 2017;2017:1856713. doi: 10.1155/2017/1856713. Epub 2017 May 25. Biomed Res Int. 2017. PMID: 28626752 Free PMC article.
This study was carried out to determine the chemoprotective potential of a polyherbal aqueous decoction comprised of Nigella sativa (seeds), Hemidesmus indicus (roots), and Smilax glabra (rhizome) against bleomycin induced cytogenetic damage in human lymphocytes. .. …
This study was carried out to determine the chemoprotective potential of a polyherbal aqueous decoction comprised of Nigella sativa (seeds), …
22 results