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Reflection on modern methods: when is a stepped-wedge cluster randomized trial a good study design choice?

Hemming K, Taljaard M. Hemming K, et al. Int J Epidemiol. 2020 Jun 1;49(3):1043-1052. doi: 10.1093/ije/dyaa077. Int J Epidemiol. 2020. PMID: 32386407 Free PMC article.

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Ethical issues in the design and conduct of stepped-wedge cluster randomized trials in low-resource settings.

Joag K, Ambrosio G, Kestler E, Weijer C, Hemming K, Van der Graaf R. Joag K, et al. Among authors: hemming k. Trials. 2019 Dec 19;20(Suppl 2):703. doi: 10.1186/s13063-019-3842-1. Trials. 2019. PMID: 31852547 Free PMC article.

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An integrated approach to improve maternal and perinatal outcomes in rural Guatemala: A stepped-wedge cluster randomized trial.

Kestler E, Ambrosio G, Hemming K, Hughes JP, Matute J, Moreno M, Madriz S, Walker D. Kestler E, et al. Among authors: hemming k. Int J Gynaecol Obstet. 2020 Oct;151(1):109-116. doi: 10.1002/ijgo.13262. Epub 2020 Jul 27. Int J Gynaecol Obstet. 2020. PMID: 32524605 Clinical Trial.

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Placental growth factor in assessment of women with suspected pre-eclampsia to reduce maternal morbidity: a stepped wedge cluster randomised control trial (PARROT Ireland).

Hayes-Ryan D, Khashan AS, Hemming K, Easter C, Devane D, Murphy DJ, Hunter A, Cotter A, McAuliffe FM, Morrison JJ, Breathnach FM, Dempsey E, Kenny LC, O'Donoghue K; PARROT Ireland trial group. Hayes-Ryan D, et al. Among authors: hemming k. BMJ. 2021 Aug 13;374:n1857. doi: 10.1136/bmj.n1857. BMJ. 2021. PMID: 34389547 Free PMC article. Clinical Trial.

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Effectiveness and cost-effectiveness of The Daily Mile on childhood weight outcomes and wellbeing: a cluster randomised controlled trial.

Breheny K, Passmore S, Adab P, Martin J, Hemming K, Lancashire ER, Frew E. Breheny K, et al. Among authors: hemming k. Int J Obes (Lond). 2020 Apr;44(4):812-822. doi: 10.1038/s41366-019-0511-0. Epub 2020 Jan 28. Int J Obes (Lond). 2020. PMID: 31988481 Free PMC article. Clinical Trial.

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Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial.

Blackwood B, Tume LN, Morris KP, Clarke M, McDowell C, Hemming K, Peters MJ, McIlmurray L, Jordan J, Agus A, Murray M, Parslow R, Walsh TS, Macrae D, Easter C, Feltbower RG, McAuley DF; SANDWICH Collaborators. Blackwood B, et al. Among authors: hemming k. JAMA. 2021 Aug 3;326(5):401-410. doi: 10.1001/jama.2021.10296. JAMA. 2021. PMID: 34342620 Free PMC article. Clinical Trial.

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Retrospective evaluation of an intervention based on training sessions to increase the use of control charts in hospitals.

Kudrna L, Bird P, Hemming K, Quinn L, Schmidtke K, Lilford R. Kudrna L, et al. Among authors: hemming k. BMJ Qual Saf. 2022 Jun 24:bmjqs-2021-013514. doi: 10.1136/bmjqs-2021-013514. Online ahead of print. BMJ Qual Saf. 2022. PMID: 35750493

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Randomized controlled trials in patients with COVID-19: a systematic review and critical appraisal.

Kudhail K, Thompson J, Mathews V, Morrison B, Hemming K. Kudhail K, et al. Among authors: hemming k. Int J Infect Dis. 2022 May 18;122:72-80. doi: 10.1016/j.ijid.2022.05.034. Online ahead of print. Int J Infect Dis. 2022. PMID: 35597556 Free PMC article.

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Mind the gap: covariate constrained randomisation can protect against substantial power loss in parallel cluster randomised trials.

Kristunas C, Grayling M, Gray LJ, Hemming K. Kristunas C, et al. Among authors: hemming k. BMC Med Res Methodol. 2022 Apr 13;22(1):111. doi: 10.1186/s12874-022-01588-8. BMC Med Res Methodol. 2022. PMID: 35413793 Free PMC article.

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Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT.

Blackwood B, Morris KP, Jordan J, McIlmurray L, Agus A, Boyle R, Clarke M, Easter C, Feltbower RG, Hemming K, Macrae D, McDowell C, Murray M, Parslow R, Peters MJ, Phair G, Tume LN, Walsh TS, McAuley DF. Blackwood B, et al. Among authors: hemming k. Health Technol Assess. 2022 Mar;26(18):1-114. doi: 10.3310/TCFX3817. Health Technol Assess. 2022. PMID: 35289741 Free article. Clinical Trial.

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