Evaluation of acute, 28-day, 13-week repeated dose oral toxicity and genotoxicity of a herbal extract (HemoHIM G) from Angelica sinensis, Ligusticum chuanxiong, and Peaonia lactiflora.
Bak SB, Choi H, Kim GD, Kim JG, Kwon DA, Kim HY, Son DW, Jeong JH, Lee BW, An HJ, Lee HS.
Bak SB, et al.
Toxicol Res. 2024 Mar 16;40(2):297-311. doi: 10.1007/s43188-024-00227-2. eCollection 2024 Apr.
Toxicol Res. 2024.
PMID: 38525135
Free PMC article.
Gross pathology, hematology, blood chemistry, and histopathology were within normal ranges, further supporting the safety of HemoHIM G. Therefore, the NOAEL of HemoHIM G was considered to be at 5000 mg/kg/day for both sexes of rats. Bacterial reverse mutation tests, …
Gross pathology, hematology, blood chemistry, and histopathology were within normal ranges, further supporting the safety of HemoHIM …