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Standardized Extract (HemoHIM) Protects against Scopolamine-Induced Amnesia in a Murine Model.
Kim SK, Kwon DA, Kim YS, Lee HS, Kim HK, Kim WK. Kim SK, et al. Evid Based Complement Alternat Med. 2021 Mar 17;2021:8884243. doi: 10.1155/2021/8884243. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 33815562 Free PMC article.
In addition, ChAT, mAchR, and CREB mRNA levels were increased in the hippocampus compared with the scopolamine group. Furthermore, HemoHIM treatment resulted in elevated BDNF protein expression. These results indicate that HemoHIM may exert antiamnesic activity by i …
In addition, ChAT, mAchR, and CREB mRNA levels were increased in the hippocampus compared with the scopolamine group. Furthermore, HemoHI
HemoHIM, a herbal preparation, alleviates airway inflammation caused by cigarette smoke and lipopolysaccharide.
Shin NR, Kim SH, Ko JW, Park SH, Lee IC, Ryu JM, Kim JC, Shin IS. Shin NR, et al. Lab Anim Res. 2017 Mar;33(1):40-47. doi: 10.5625/lar.2017.33.1.40. Epub 2017 Mar 27. Lab Anim Res. 2017. PMID: 28400838 Free PMC article.
HemoHIM, herbal preparation has designed for immune system recovery. We investigated the anti-inflammatory effect of HemoHIM on cigarette smoke (CS) and lipopolysaccharide (LPS) induced chronic obstructive pulmonary disease (COPD) mouse model. ...Therefore, we sugge
HemoHIM, herbal preparation has designed for immune system recovery. We investigated the anti-inflammatory effect of HemoHIM o
HemoHIM enhances the therapeutic efficacy of ionizing radiation treatment in tumor-bearing mice.
Park HR, Ju EJ, Jo SK, Jung U, Kim SH. Park HR, et al. J Med Food. 2010 Feb;13(1):47-53. doi: 10.1089/jmf.2009.1049. J Med Food. 2010. PMID: 20136435
In addition, HemoHIM administration increased the interleukin-2 and tumor necrosis factor-alpha secretion from lymphocytes stimulated with concanavalin A, which seemed to contribute to the enhanced efficacy of HemoHIM in tumor-bearing mice treated with IR. In conclu …
In addition, HemoHIM administration increased the interleukin-2 and tumor necrosis factor-alpha secretion from lymphocytes stimulated …
Preventive Effect of the Herbal Preparation, HemoHIM, on Cisplatin-Induced Immune Suppression.
Kim SK, Kwon DA, Lee HS, Kim HK, Kim WK. Kim SK, et al. Evid Based Complement Alternat Med. 2019 Mar 20;2019:3494806. doi: 10.1155/2019/3494806. eCollection 2019. Evid Based Complement Alternat Med. 2019. PMID: 31015850 Free PMC article.
We determined the functional effect of the herbal preparation, HemoHIM, on the immune system, by examining the immunomodulatory activities of HemoHIM using immunocompromised mice. ...Mice were injected intraperitoneally with cisplatin, an immunosuppressive anticance …
We determined the functional effect of the herbal preparation, HemoHIM, on the immune system, by examining the immunomodulatory activ …
Antioxidant and Anti-Fatigue Effects of a Standardized Botanical Extract Fraction (HemoHIM) in Forced-Exercised Aged Mice.
Kwon DA, Bak SB, Kim YS, Kim SK, Lee HS. Kwon DA, et al. J Med Food. 2024 Jun;27(6):502-509. doi: 10.1089/jmf.2023.K.0234. Epub 2024 Apr 25. J Med Food. 2024. PMID: 38669056 Free article.
This study aimed to research the potential antioxidant effects of HemoHIM and its capacity for reducing fatigue in aged mice subjected to forced exercise. After administering HemoHIM 125 (500 mg/kg orally) for 4 weeks in 8-month-old female C57BL/6 mice (4 groups of …
This study aimed to research the potential antioxidant effects of HemoHIM and its capacity for reducing fatigue in aged mice subjecte …
Antioxidant and antifatigue effect of a standardized fraction (HemoHIM) from Angelica gigas, Cnidium officinale, and Paeonia lactiflora.
Kwon DA, Kim YS, Kim SK, Baek SH, Kim HK, Lee HS. Kwon DA, et al. Pharm Biol. 2021 Dec;59(1):391-400. doi: 10.1080/13880209.2021.1900878. Pharm Biol. 2021. PMID: 33813987 Free PMC article.
To date, studies on the antifatigue effects of HemoHIM have not been conducted. OBJECTIVE: The antifatigue effects of HemoHIM using models of citrinin and exercise-induced chronic fatigue syndrome were investigated. ...In vivo, HemoHIM significantly improved …
To date, studies on the antifatigue effects of HemoHIM have not been conducted. OBJECTIVE: The antifatigue effects of HemoHIM
Protective effects of HemoHIM on immune and hematopoietic systems against gamma-irradiation.
Park HR, Jo SK, Jung U, Yee ST, Kim SH. Park HR, et al. Phytother Res. 2014 Feb;28(2):245-51. doi: 10.1002/ptr.4982. Epub 2013 Apr 18. Phytother Res. 2014. PMID: 23595637
The HemoHIM administration decreased the apoptosis of bone marrow cells in irradiated mice. On the other hand, HemoHIM increased the formation of endogenous spleen colony in irradiated mice. In irradiated mice, the recovery of total leukocytes in the peripheral bloo …
The HemoHIM administration decreased the apoptosis of bone marrow cells in irradiated mice. On the other hand, HemoHIM increas …
Evaluation of acute, 28-day, 13-week repeated dose oral toxicity and genotoxicity of a herbal extract (HemoHIM G) from Angelica sinensis, Ligusticum chuanxiong, and Peaonia lactiflora.
Bak SB, Choi H, Kim GD, Kim JG, Kwon DA, Kim HY, Son DW, Jeong JH, Lee BW, An HJ, Lee HS. Bak SB, et al. Toxicol Res. 2024 Mar 16;40(2):297-311. doi: 10.1007/s43188-024-00227-2. eCollection 2024 Apr. Toxicol Res. 2024. PMID: 38525135 Free PMC article.
Gross pathology, hematology, blood chemistry, and histopathology were within normal ranges, further supporting the safety of HemoHIM G. Therefore, the NOAEL of HemoHIM G was considered to be at 5000 mg/kg/day for both sexes of rats. Bacterial reverse mutation tests, …
Gross pathology, hematology, blood chemistry, and histopathology were within normal ranges, further supporting the safety of HemoHIM
Protective effects of a standardized extract (HemoHIM) using indomethacin- and ethanol/HCl-induced gastric mucosal injury models.
Kwon DA, Kim YS, Baek SH, Kim SK, Kim HK, Jo SK, Jung U, Park HR, Lee HS. Kwon DA, et al. Pharm Biol. 2019 Dec;57(1):543-549. doi: 10.1080/13880209.2019.1651875. Pharm Biol. 2019. PMID: 31429615 Free PMC article.
HemoHIM has been investigated for its ability to enhance tissue self-renewal and stimulate immune systems. ...H&E staining of the gastric mucosa showed decreased erosion and hemorrhage in HemoHIM group compared to EtOH/HCl group. Discussion and conclusions: Base
HemoHIM has been investigated for its ability to enhance tissue self-renewal and stimulate immune systems. ...H&E staining of the
25 results