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Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death.
Duplan L, Bernard N, Casseron W, Dudley K, Thouvenot E, Honnorat J, Rogemond V, De Bovis B, Aebischer P, Marin P, Raoul C, Henderson CE, Pettmann B. Duplan L, et al. Among authors: henderson ce. J Neurosci. 2010 Jan 13;30(2):785-96. doi: 10.1523/JNEUROSCI.5411-09.2010. J Neurosci. 2010. PMID: 20071543 Free PMC article.
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