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221 results
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The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis.
Liang J, Shao SH, Xu ZX, Hennessy B, Ding Z, Larrea M, Kondo S, Dumont DJ, Gutterman JU, Walker CL, Slingerland JM, Mills GB. Liang J, et al. Among authors: Hennessy B. Nat Cell Biol. 2007 Feb;9(2):218-24. doi: 10.1038/ncb1537. Epub 2007 Jan 21. Nat Cell Biol. 2007. PMID: 17237771
Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors.
Kim WY, Prudkin L, Feng L, Kim ES, Hennessy B, Lee JS, Lee JJ, Glisson B, Lippman SM, Wistuba II, Hong WK, Lee HY. Kim WY, et al. Among authors: Hennessy B. Cancer. 2012 Aug 15;118(16):3993-4003. doi: 10.1002/cncr.26656. Epub 2012 Feb 22. Cancer. 2012. PMID: 22359227 Free PMC article.
Genome-wide transcriptome profiling of homologous recombination DNA repair.
Peng G, Chun-Jen Lin C, Mo W, Dai H, Park YY, Kim SM, Peng Y, Mo Q, Siwko S, Hu R, Lee JS, Hennessy B, Hanash S, Mills GB, Lin SY. Peng G, et al. Among authors: Hennessy B. Nat Commun. 2014;5:3361. doi: 10.1038/ncomms4361. Nat Commun. 2014. PMID: 24553445 Free PMC article.
A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy.
Kim WY, Chang DJ, Hennessy B, Kang HJ, Yoo J, Han SH, Kim YS, Park HJ, Seo SY, Mills G, Kim KW, Hong WK, Suh YG, Lee HY. Kim WY, et al. Among authors: Hennessy B. Cancer Prev Res (Phila). 2008 Dec;1(7):577-87. doi: 10.1158/1940-6207.CAPR-08-0184. Cancer Prev Res (Phila). 2008. PMID: 19139008 Free PMC article.
The biology of ovarian cancer: new opportunities for translation.
Bast RC Jr, Hennessy B, Mills GB. Bast RC Jr, et al. Among authors: Hennessy B. Nat Rev Cancer. 2009 Jun;9(6):415-28. doi: 10.1038/nrc2644. Nat Rev Cancer. 2009. PMID: 19461667 Free PMC article. Review.
Point mutations of protein kinases and individualised cancer therapy.
Davies M, Hennessy B, Mills GB. Davies M, et al. Among authors: Hennessy B. Expert Opin Pharmacother. 2006 Nov;7(16):2243-61. doi: 10.1517/14656566.7.16.2243. Expert Opin Pharmacother. 2006. PMID: 17059381 Review.
c-Jun-NH2-kinase-1 inhibition leads to antitumor activity in ovarian cancer.
Vivas-Mejia P, Benito JM, Fernandez A, Han HD, Mangala L, Rodriguez-Aguayo C, Chavez-Reyes A, Lin YG, Carey MS, Nick AM, Stone RL, Kim HS, Claret FX, Bornmann W, Hennessy BT, Sanguino A, Peng Z, Sood AK, Lopez-Berestein G. Vivas-Mejia P, et al. Among authors: Hennessy BT. Clin Cancer Res. 2010 Jan 1;16(1):184-94. doi: 10.1158/1078-0432.CCR-09-1180. Epub 2009 Dec 22. Clin Cancer Res. 2010. PMID: 20028751 Free PMC article.
High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability.
Cheung LW, Hennessy BT, Li J, Yu S, Myers AP, Djordjevic B, Lu Y, Stemke-Hale K, Dyer MD, Zhang F, Ju Z, Cantley LC, Scherer SE, Liang H, Lu KH, Broaddus RR, Mills GB. Cheung LW, et al. Among authors: Hennessy BT. Cancer Discov. 2011 Jul;1(2):170-85. doi: 10.1158/2159-8290.CD-11-0039. Epub 2011 Jun 7. Cancer Discov. 2011. PMID: 21984976 Free PMC article.
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.
Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA. Vasudevan KM, et al. Among authors: Hennessy BT. Cancer Cell. 2009 Jul 7;16(1):21-32. doi: 10.1016/j.ccr.2009.04.012. Cancer Cell. 2009. PMID: 19573809 Free PMC article.
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