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Nonsense-mediated decay approaches the clinic.
Holbrook JA, Neu-Yilik G, Hentze MW, Kulozik AE. Holbrook JA, et al. Among authors: hentze mw. Nat Genet. 2004 Aug;36(8):801-8. doi: 10.1038/ng1403. Nat Genet. 2004. PMID: 15284851 Review.
Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.
Mleczko-Sanecka K, Roche F, da Silva AR, Call D, D'Alessio F, Ragab A, Lapinski PE, Ummanni R, Korf U, Oakes C, Damm G, D'Alessandro LA, Klingmüller U, King PD, Boutros M, Hentze MW, Muckenthaler MU. Mleczko-Sanecka K, et al. Among authors: hentze mw. Blood. 2014 Mar 6;123(10):1574-85. doi: 10.1182/blood-2013-07-515957. Epub 2014 Jan 2. Blood. 2014. PMID: 24385536 Free PMC article.
The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion.
Hollerer I, Curk T, Haase B, Benes V, Hauer C, Neu-Yilik G, Bhuvanagiri M, Hentze MW, Kulozik AE. Hollerer I, et al. Among authors: hentze mw. RNA. 2016 Sep;22(9):1441-53. doi: 10.1261/rna.055657.115. Epub 2016 Jul 12. RNA. 2016. PMID: 27407180 Free PMC article.
p38 MAPK controls prothrombin expression by regulated RNA 3' end processing.
Danckwardt S, Gantzert AS, Macher-Goeppinger S, Probst HC, Gentzel M, Wilm M, Gröne HJ, Schirmacher P, Hentze MW, Kulozik AE. Danckwardt S, et al. Among authors: hentze mw. Mol Cell. 2011 Feb 4;41(3):298-310. doi: 10.1016/j.molcel.2010.12.032. Mol Cell. 2011. PMID: 21292162
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