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Quorum sensing : a novel target for the treatment of biofilm infections.
Hentzer M, Eberl L, Nielsen J, Givskov M. Hentzer M, et al. BioDrugs. 2003;17(4):241-50. doi: 10.2165/00063030-200317040-00003. BioDrugs. 2003. PMID: 12899641 Review.
Quorum sensing regulation in Aeromonas hydrophila.
Garde C, Bjarnsholt T, Givskov M, Jakobsen TH, Hentzer M, Claussen A, Sneppen K, Ferkinghoff-Borg J, Sams T. Garde C, et al. J Mol Biol. 2010 Mar 5;396(4):849-57. doi: 10.1016/j.jmb.2010.01.002. Epub 2010 Jan 11. J Mol Biol. 2010. PMID: 20064524
Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors.
Yang L, Rybtke MT, Jakobsen TH, Hentzer M, Bjarnsholt T, Givskov M, Tolker-Nielsen T. Yang L, et al. Antimicrob Agents Chemother. 2009 Jun;53(6):2432-43. doi: 10.1128/AAC.01283-08. Epub 2009 Apr 13. Antimicrob Agents Chemother. 2009. PMID: 19364871 Free PMC article.
Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector.
Rasmussen TB, Bjarnsholt T, Skindersoe ME, Hentzer M, Kristoffersen P, Köte M, Nielsen J, Eberl L, Givskov M. Rasmussen TB, et al. J Bacteriol. 2005 Mar;187(5):1799-814. doi: 10.1128/JB.187.5.1799-1814.2005. J Bacteriol. 2005. PMID: 15716452 Free PMC article.
The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional.
Shrout JD, Chopp DL, Just CL, Hentzer M, Givskov M, Parsek MR. Shrout JD, et al. Mol Microbiol. 2006 Dec;62(5):1264-77. doi: 10.1111/j.1365-2958.2006.05421.x. Epub 2006 Oct 24. Mol Microbiol. 2006. PMID: 17059568
Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections.
Bjarnsholt T, Jensen PØ, Rasmussen TB, Christophersen L, Calum H, Hentzer M, Hougen HP, Rygaard J, Moser C, Eberl L, Høiby N, Givskov M. Bjarnsholt T, et al. Microbiology (Reading). 2005 Dec;151(Pt 12):3873-3880. doi: 10.1099/mic.0.27955-0. Microbiology (Reading). 2005. PMID: 16339933
Identity and effects of quorum-sensing inhibitors produced by Penicillium species.
Rasmussen TB, Skindersoe ME, Bjarnsholt T, Phipps RK, Christensen KB, Jensen PO, Andersen JB, Koch B, Larsen TO, Hentzer M, Eberl L, Hoiby N, Givskov M. Rasmussen TB, et al. Microbiology (Reading). 2005 May;151(Pt 5):1325-1340. doi: 10.1099/mic.0.27715-0. Microbiology (Reading). 2005. PMID: 15870443
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis.
Hoffmann N, Rasmussen TB, Jensen PØ, Stub C, Hentzer M, Molin S, Ciofu O, Givskov M, Johansen HK, Høiby N. Hoffmann N, et al. Infect Immun. 2005 Apr;73(4):2504-14. doi: 10.1128/IAI.73.4.2504-2514.2005. Infect Immun. 2005. PMID: 15784597 Free PMC article.
Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent.
Bjarnsholt T, Jensen PØ, Burmølle M, Hentzer M, Haagensen JAJ, Hougen HP, Calum H, Madsen KG, Moser C, Molin S, Høiby N, Givskov M. Bjarnsholt T, et al. Microbiology (Reading). 2005 Feb;151(Pt 2):373-383. doi: 10.1099/mic.0.27463-0. Microbiology (Reading). 2005. PMID: 15699188
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