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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1927 5
1928 1
1929 1
1933 2
1935 1
1936 2
1937 2
1938 5
1939 5
1940 10
1941 9
1942 7
1943 6
1944 1
1945 20
1946 37
1947 75
1948 80
1949 76
1950 158
1951 148
1952 181
1953 216
1954 249
1955 220
1956 249
1957 233
1958 181
1959 202
1960 212
1961 221
1962 242
1963 414
1964 677
1965 430
1966 444
1967 612
1968 692
1969 751
1970 717
1971 813
1972 847
1973 1041
1974 986
1975 1047
1976 1016
1977 1088
1978 932
1979 1028
1980 1077
1981 1108
1982 1091
1983 1202
1984 1320
1985 1424
1986 1518
1987 1538
1988 1647
1989 1882
1990 1961
1991 2198
1992 2217
1993 2300
1994 2253
1995 2338
1996 2493
1997 2524
1998 2551
1999 2631
2000 2559
2001 2681
2002 2609
2003 2630
2004 2703
2005 2676
2006 2594
2007 2625
2008 2756
2009 2782
2010 2934
2011 2913
2012 2981
2013 2926
2014 2961
2015 2894
2016 2879
2017 2833
2018 2672
2019 2603
2020 3334
2021 3439
2022 2996
2023 309
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112,599 results
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Page 1
Heparin and anticoagulation.
Onishi A, St Ange K, Dordick JS, Linhardt RJ. Onishi A, et al. Front Biosci (Landmark Ed). 2016 Jun 1;21(7):1372-92. doi: 10.2741/4462. Front Biosci (Landmark Ed). 2016. PMID: 27100512 Free article. Review.
Heparin's structures and its biological and therapeutic roles are discussed. Particular emphasis is placed on heparin's therapeutic application and its adverse effects. The future prospects are excellent for new heparins and new heparin-b …
Heparin's structures and its biological and therapeutic roles are discussed. Particular emphasis is placed on heparin' …
Heparin.
[No authors listed] [No authors listed] 2020 Nov 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2020 Nov 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999980 Free Books & Documents. Review.
Although heparin itself has not been studied, low molecular weight heparins (e.g., dalteparin, enoxaparin) are not excreted into breastmilk in clinically relevant amounts. Because heparin has an even higher molecular weight of 3000 to 30,000 daltons, it would …
Although heparin itself has not been studied, low molecular weight heparins (e.g., dalteparin, enoxaparin) are not excreted in …
Heparin: what is it? How does it work?
Schwartz BS. Schwartz BS. Clin Cardiol. 1990 Apr;13(4 Suppl 6):VI12-5. Clin Cardiol. 1990. PMID: 2191809 Free article. Review.
The anticoagulant agent heparin inhibits thrombosis by interacting with antithrombin III. ...Separate from the chemical elements are three unique domains of activity that have been defined based on the functional interaction of heparin with antithrombin III. Bleedin …
The anticoagulant agent heparin inhibits thrombosis by interacting with antithrombin III. ...Separate from the chemical elements are …
The Anticoagulant and Nonanticoagulant Properties of Heparin.
Beurskens DMH, Huckriede JP, Schrijver R, Hemker HC, Reutelingsperger CP, Nicolaes GAF. Beurskens DMH, et al. Thromb Haemost. 2020 Oct;120(10):1371-1383. doi: 10.1055/s-0040-1715460. Epub 2020 Aug 20. Thromb Haemost. 2020. PMID: 32820487 Review.
Heparins represent one of the most frequently used pharmacotherapeutics. ...In this review we focus on the anticoagulant and nonanticoagulant activities of heparin and, where possible, discuss the underlying molecular mechanisms that explain the diversity of hepa …
Heparins represent one of the most frequently used pharmacotherapeutics. ...In this review we focus on the anticoagulant and nonantic …
Heparin: An old drug for new clinical applications.
Wang P, Chi L, Zhang Z, Zhao H, Zhang F, Linhardt RJ. Wang P, et al. Carbohydr Polym. 2022 Nov 1;295:119818. doi: 10.1016/j.carbpol.2022.119818. Epub 2022 Jul 3. Carbohydr Polym. 2022. PMID: 35989029 Review.
Heparin, an old but first-line anticoagulant, has been used over a century. It is a heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution in relative molecular weight and charge density. These structural properties allow heparin …
Heparin, an old but first-line anticoagulant, has been used over a century. It is a heterogeneous, linear, highly sulfated, anionic g …
Heparin: role in protein purification and substitution with animal-component free material.
Bolten SN, Rinas U, Scheper T. Bolten SN, et al. Appl Microbiol Biotechnol. 2018 Oct;102(20):8647-8660. doi: 10.1007/s00253-018-9263-3. Epub 2018 Aug 9. Appl Microbiol Biotechnol. 2018. PMID: 30094590 Free PMC article. Review.
These properties are employed in several therapeutic drugs. Heparin's activities are associated with its interaction to various proteins. ...This review examines strategies to avoid these disadvantages. Thereby, alternatives for the provision of heparin such …
These properties are employed in several therapeutic drugs. Heparin's activities are associated with its interaction to variou …
Heparin structure.
Casu B. Casu B. Haemostasis. 1990;20 Suppl 1:62-73. doi: 10.1159/000216162. Haemostasis. 1990. PMID: 2083874 Review.
Heparins used in therapy are largely constituted by sequences of the trisulfated disaccharide L-iduronic acid-2-sulfate----D-glucosamine-N,6-disulfate. These regular sequences are interrupted by undersulfated (occasionally, oversulfated) sequences containing D-glucuronic a …
Heparins used in therapy are largely constituted by sequences of the trisulfated disaccharide L-iduronic acid-2-sulfate----D-glucosam …
[Heparin].
Aiach M, Fiessinger JN, Chousterman M. Aiach M, et al. Rev Prat. 1977 Dec 11;27(57):3953-74. Rev Prat. 1977. PMID: 345399 Review. French. No abstract available.
Antithrombogenic heparin-bound polyurethanes.
Ito Y. Ito Y. J Biomater Appl. 1987 Oct;2(2):235-65. doi: 10.1177/088532828700200204. J Biomater Appl. 1987. PMID: 3333067 Review.
It is useful to modify this material by heparinization. Several approaches to heparinization have been devised: 1) a general method of heparinization, applicable to all polymeric materials, 2) a heparinization method specific to polyurethanes, and 3) t …
It is useful to modify this material by heparinization. Several approaches to heparinization have been devised: 1) a general m …
Re-visiting the structure of heparin.
Casu B, Naggi A, Torri G. Casu B, et al. Carbohydr Res. 2015 Feb 11;403:60-8. doi: 10.1016/j.carres.2014.06.023. Epub 2014 Jul 3. Carbohydr Res. 2015. PMID: 25088334 Review.
The sulfated polysaccharide heparin has been used as a life-saving anticoagulant in clinics well before its detailed structure was known. This mini-review is a survey of the evolution in the discovery of the primary and secondary structure of heparin. Highlights in …
The sulfated polysaccharide heparin has been used as a life-saving anticoagulant in clinics well before its detailed structure was kn …
112,599 results
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