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The telomerase inhibitor imetelstat alone, and in combination with trastuzumab, decreases the cancer stem cell population and self-renewal of HER2+ breast cancer cells.
Koziel JE, Herbert BS. Koziel JE, et al. Among authors: herbert bs. Breast Cancer Res Treat. 2015 Feb;149(3):607-18. doi: 10.1007/s10549-015-3270-1. Epub 2015 Jan 28. Breast Cancer Res Treat. 2015. PMID: 25627551 Free PMC article.
Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.
Subbaramaiah K, Brown KA, Zahid H, Balmus G, Weiss RS, Herbert BS, Dannenberg AJ. Subbaramaiah K, et al. Among authors: herbert bs. J Biol Chem. 2016 Jul 29;291(31):16011-23. doi: 10.1074/jbc.M115.698902. Epub 2016 Jun 1. J Biol Chem. 2016. PMID: 27467582 Free PMC article. Retracted.
p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling.
Kochhar A, Kopelovich L, Sue E, Guttenplan JB, Herbert BS, Dannenberg AJ, Subbaramaiah K. Kochhar A, et al. Among authors: herbert bs. Cancer Prev Res (Phila). 2014 Jun;7(6):596-606. doi: 10.1158/1940-6207.CAPR-14-0051. Epub 2014 Apr 15. Cancer Prev Res (Phila). 2014. PMID: 24736433 Free PMC article.
Resveratrol augments paclitaxel treatment in MDA-MB-231 and paclitaxel-resistant MDA-MB-231 breast cancer cells.
Sprouse AA, Herbert BS. Sprouse AA, et al. Among authors: herbert bs. Anticancer Res. 2014 Oct;34(10):5363-74. Anticancer Res. 2014. PMID: 25275030
Selective inhibition of pancreatic ductal adenocarcinoma cell growth by the mitotic MPS1 kinase inhibitor NMS-P715.
Slee RB, Grimes BR, Bansal R, Gore J, Blackburn C, Brown L, Gasaway R, Jeong J, Victorino J, March KL, Colombo R, Herbert BS, Korc M. Slee RB, et al. Among authors: herbert bs. Mol Cancer Ther. 2014 Feb;13(2):307-315. doi: 10.1158/1535-7163.MCT-13-0324. Epub 2013 Nov 26. Mol Cancer Ther. 2014. PMID: 24282275 Free PMC article.
Cell-type-specific responses to chemotherapeutics in breast cancer.
Troester MA, Hoadley KA, Sørlie T, Herbert BS, Børresen-Dale AL, Lønning PE, Shay JW, Kaufmann WK, Perou CM. Troester MA, et al. Among authors: herbert bs. Cancer Res. 2004 Jun 15;64(12):4218-26. doi: 10.1158/0008-5472.CAN-04-0107. Cancer Res. 2004. PMID: 15205334
Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer.
Hochreiter AE, Xiao H, Goldblatt EM, Gryaznov SM, Miller KD, Badve S, Sledge GW, Herbert BS. Hochreiter AE, et al. Among authors: herbert bs. Clin Cancer Res. 2006 May 15;12(10):3184-92. doi: 10.1158/1078-0432.CCR-05-2760. Clin Cancer Res. 2006. PMID: 16707619
Immortalization and characterization of osteoblast cell lines generated from wild-type and Nmp4-null mouse bone marrow stromal cells using murine telomerase reverse transcriptase (mTERT).
Alvarez MB, Childress P, Philip BK, Gerard-O'Riley R, Hanlon M, Herbert BS, Robling AG, Pavalko FM, Bidwell JP. Alvarez MB, et al. Among authors: herbert bs. J Cell Physiol. 2012 May;227(5):1873-82. doi: 10.1002/jcp.22915. J Cell Physiol. 2012. PMID: 21732358 Free PMC article.
Medical genetics and epigenetics of telomerase.
Koziel JE, Fox MJ, Steding CE, Sprouse AA, Herbert BS. Koziel JE, et al. Among authors: herbert bs. J Cell Mol Med. 2011 Mar;15(3):457-67. doi: 10.1111/j.1582-4934.2011.01276.x. J Cell Mol Med. 2011. PMID: 21323862 Free PMC article. Review.
A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1.
Herbert BS, Grimes BR, Xu WM, Werner M, Ward C, Rossetti S, Harris P, Bello-Reuss E, Ward HH, Miller C, Gattone VH 2nd, Phillips CL, Wandinger-Ness A, Bacallao RL. Herbert BS, et al. PLoS One. 2013;8(1):e55191. doi: 10.1371/journal.pone.0055191. Epub 2013 Jan 28. PLoS One. 2013. PMID: 23383103 Free PMC article.
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